Journal ArticleDOI
Creating, transporting, cutting, and merging liquid droplets by electrowetting-based actuation for digital microfluidic circuits
TLDR
In this paper, the authors report the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting.Abstract:
Reports the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting, i.e., controlling the wetting property of the surface through electric potential. The surface used in this report is, more specifically, an electrode covered with dielectrics, hence, called electrowetting-on-dielectric (EWOD). All the fluidic movement is confined between two plates, which we call parallel-plate channel, rather than through closed channels or on open surfaces. While transporting and merging droplets are easily verified, we discover that there exists a design criterion for a given set of materials beyond which the droplet simply cannot be cut by EWOD mechanism. The condition for successful cutting is theoretically analyzed by examining the channel gap, the droplet size and the degree of contact angle change by electrowetting on dielectric (EWOD). A series of experiments is run and verifies the criterion.read more
Citations
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Journal ArticleDOI
Liquid Lenses and Driving Mechanisms: A Review
Cheng-Pu Chiu,Tsai-Jung Chiang,Jem-Kun Chen,Feng-Chih Chang,Fu-Hsiang Ko,Chih-Wei Chu,Shiao-Wei Kuo,Shih-Kang Fan +7 more
TL;DR: In this paper, the authors discuss liquid lenses driven by various mechanisms and categorize the driving mechanisms into mechanical and electrical ones, i.e., mechanical driving with an elastic membrane and an external pump drives liquids in a cavity by controlling the hydraulic pressure.
Journal ArticleDOI
Chaotic mixing in thermocapillary-driven microdroplets
TL;DR: In this paper, the authors demonstrate that quick and thorough mixing inside a spherical microdroplet suspended in a layer of substrate fluid can be obtained by moving the droplet along a two-dimensional path using temperature-induced surface tension gradients.
Patent
Methods and devices for high fidelity polynucleotide synthesis
TL;DR: In this paper, the authors present methods for synthesizing and assembling at least one polynucleotide product having a predefined sequence from a plurality of different oligonucleotides.
Journal ArticleDOI
Condensation on surface energy gradient shifts drop size distribution toward small drops.
TL;DR: This study examines how chemical modification of a cooled surface affects drop growth and coalescence, which in turn influences how a population of drops evolves, which contributes to the high heat transfer coefficients in dropwise condensation.
Journal ArticleDOI
Asymmetric electrowetting—moving droplets by a square wave
TL;DR: Here droplet oscillation and continuous pumping are demonstrated by asymmetric electrowetting on an open surface with embedded electrodes powered by a square wave electrical signal without control circuits to demonstrate manipulation capability on anopen surface.
References
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Book
Fundamentals of microfabrication
TL;DR: The second edition of the Fundamentals of Microfabrication as discussed by the authors provides an in-depth coverage of the science of miniaturization, its methods, and materials, from the fundamentals of lithography through bonding and packaging to quantum structures and molecular engineering.
Journal ArticleDOI
Electrowetting-based actuation of liquid droplets for microfluidic applications
TL;DR: In this article, a microactuator for rapid manipulation of discrete microdroplets is presented, which is accomplished by direct electrical control of the surface tension through two sets of opposing planar electrodes fabricated on glass.
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Micromachined Transducers Sourcebook
TL;DR: In this paper, the authors present an overview of Micromachining Techniques, Mechanical Transducers, Optical Transducers and Ionizing Radiation Transducers for Microfluidic Devices.
Journal ArticleDOI
Electrowetting-based actuation of droplets for integrated microfluidics
TL;DR: In this paper, an alternative approach to microfluidics based upon the micromanipulation of discrete droplets of aqueous electrolyte by electrowetting is reported.