Journal ArticleDOI
Creating, transporting, cutting, and merging liquid droplets by electrowetting-based actuation for digital microfluidic circuits
TLDR
In this paper, the authors report the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting.Abstract:
Reports the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting, i.e., controlling the wetting property of the surface through electric potential. The surface used in this report is, more specifically, an electrode covered with dielectrics, hence, called electrowetting-on-dielectric (EWOD). All the fluidic movement is confined between two plates, which we call parallel-plate channel, rather than through closed channels or on open surfaces. While transporting and merging droplets are easily verified, we discover that there exists a design criterion for a given set of materials beyond which the droplet simply cannot be cut by EWOD mechanism. The condition for successful cutting is theoretically analyzed by examining the channel gap, the droplet size and the degree of contact angle change by electrowetting on dielectric (EWOD). A series of experiments is run and verifies the criterion.read more
Citations
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Journal ArticleDOI
Rapid, Self-driven Liquid Mixing on Open-Surface Microfluidic Platforms.
Jared Morrissette,Pallab Sinha Mahapatra,Aritra Ghosh,Ranjan Ganguly,Constantine M. Megaridis +4 more
TL;DR: This study presents a SDSM fabricated by strategically patterning three wettable wedge-shaped tracks onto a non-wettable, flat surface, and offers design insights for developing low-cost surface microfluidic mixing devices on open substrates.
Journal ArticleDOI
Online coupling of digital microfluidic devices with mass spectrometry detection using an eductor with electrospray ionization.
TL;DR: An eductor is demonstrated which facilitated online coupling of DMF with electrospray ionization MS detection and has the potential for rapid, versatile, and high-throughput microfluidic analyses.
Journal ArticleDOI
Statics and dynamics of electrowetting on pillar-arrayed surfaces at the nanoscale
Ya-Pu Zhao,Quanzi Yuan +1 more
TL;DR: Based on the molecular kinetic theory and the wetting states, theoretical models have been proposed to comprehend the physical mechanisms in the statics and dynamics of electrowetting, and are validated by the simulations.
Journal ArticleDOI
Enhanced mixing of droplets during coalescence on a surface with a wettability gradient.
TL;DR: 3D scans demonstrate that the motion of the contact line during coalescence distributes the fluids in a complicated manner, thus beneficial for mixing, and is applicable also for platforms other than a surface with a wettability gradient.
Journal ArticleDOI
A unified platform for optoelectrowetting and optoelectronic tweezers
TL;DR: A platform capable of seamlessly unifying bothoptoelectrowetting and optoelectronic tweezers is presented, which enables the user to manipulate aqueous droplets as well as individual particles within those droplets (with dielectrophoresis).
References
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Fundamentals of microfabrication
TL;DR: The second edition of the Fundamentals of Microfabrication as discussed by the authors provides an in-depth coverage of the science of miniaturization, its methods, and materials, from the fundamentals of lithography through bonding and packaging to quantum structures and molecular engineering.
Journal ArticleDOI
Electrowetting-based actuation of liquid droplets for microfluidic applications
TL;DR: In this article, a microactuator for rapid manipulation of discrete microdroplets is presented, which is accomplished by direct electrical control of the surface tension through two sets of opposing planar electrodes fabricated on glass.
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Micromachined Transducers Sourcebook
TL;DR: In this paper, the authors present an overview of Micromachining Techniques, Mechanical Transducers, Optical Transducers and Ionizing Radiation Transducers for Microfluidic Devices.
Journal ArticleDOI
Electrowetting-based actuation of droplets for integrated microfluidics
TL;DR: In this paper, an alternative approach to microfluidics based upon the micromanipulation of discrete droplets of aqueous electrolyte by electrowetting is reported.