Journal ArticleDOI
Creating, transporting, cutting, and merging liquid droplets by electrowetting-based actuation for digital microfluidic circuits
TLDR
In this paper, the authors report the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting.Abstract:
Reports the completion of four fundamental fluidic operations considered essential to build digital microfluidic circuits, which can be used for lab-on-a-chip or micro total analysis system (/spl mu/TAS): 1) creating, 2) transporting, 3) cutting, and 4) merging liquid droplets, all by electrowetting, i.e., controlling the wetting property of the surface through electric potential. The surface used in this report is, more specifically, an electrode covered with dielectrics, hence, called electrowetting-on-dielectric (EWOD). All the fluidic movement is confined between two plates, which we call parallel-plate channel, rather than through closed channels or on open surfaces. While transporting and merging droplets are easily verified, we discover that there exists a design criterion for a given set of materials beyond which the droplet simply cannot be cut by EWOD mechanism. The condition for successful cutting is theoretically analyzed by examining the channel gap, the droplet size and the degree of contact angle change by electrowetting on dielectric (EWOD). A series of experiments is run and verifies the criterion.read more
Citations
More filters
Journal ArticleDOI
Direct heating of aqueous droplets using high frequency voltage signals on an EWOD platform
Krishnadas Narayanan Nampoothiri,Mahadevan Subramanya Seshasayee,Vinod Srinivasan,M. S. Bobji,Prosenjit Sen +4 more
TL;DR: In this article, the authors demonstrate a new technique of heating aqueous droplets on conventional EWOD electrodes by using high frequency high-voltage AC signals, which can achieve temperatures of 93-94 degrees C.
Proceedings ArticleDOI
Optimal scheduling of biochemical analyses on digital microfluidic systems
Lingzhi Luo,Srinivas Akella +1 more
TL;DR: This paper considers a binary tree representation of chemical analyses to schedule operations, and uses pipelining to find the lower bound of the mixing completion time according to the tree structure of given reactions, and calculates the minimal number of mixers required.
Journal ArticleDOI
Liquid microdroplet sliding on hydrophobic surfaces in the presence of an electric field.
TL;DR: Experimental results show that lateral friction force linearly increases with increasing droplet diameters, which can be explained by a droplet sliding model.
Journal ArticleDOI
In situ characterization of microdroplet interfacial properties in digital microfluidic systems
TL;DR: The proposed characterization method relies on two submodules, namely the contact angle and capacitance sampling sub modules, in a digital microfluidic system to characterize the interfacial properties of a microdroplet containing an aqueous solution of bovine serum albumin in which adsorption is a predominant effect.
Journal ArticleDOI
Low Voltage Electrowetting on Ferroelectric PVDF-HFP Insulator with Highly Tunable Contact Angle Range.
TL;DR: It is shown that a thin bilayer exhibits contact angle modulation of Δθ (U) ≈ 60° at merely 15 V amplitude of AC voltage indicating a potential dielectric for practical low voltage electrowetting applications.
References
More filters
Book
Fundamentals of microfabrication
TL;DR: The second edition of the Fundamentals of Microfabrication as discussed by the authors provides an in-depth coverage of the science of miniaturization, its methods, and materials, from the fundamentals of lithography through bonding and packaging to quantum structures and molecular engineering.
Journal ArticleDOI
Electrowetting-based actuation of liquid droplets for microfluidic applications
TL;DR: In this article, a microactuator for rapid manipulation of discrete microdroplets is presented, which is accomplished by direct electrical control of the surface tension through two sets of opposing planar electrodes fabricated on glass.
Book
Micromachined Transducers Sourcebook
TL;DR: In this paper, the authors present an overview of Micromachining Techniques, Mechanical Transducers, Optical Transducers and Ionizing Radiation Transducers for Microfluidic Devices.
Journal ArticleDOI
Electrowetting-based actuation of droplets for integrated microfluidics
TL;DR: In this paper, an alternative approach to microfluidics based upon the micromanipulation of discrete droplets of aqueous electrolyte by electrowetting is reported.