Journal ArticleDOI
Flexible Graphene Solution-Gated Field-Effect Transistors: Efficient Transducers for Micro-Electrocorticography
Clément Hébert,Eduard Masvidal-Codina,Alejandro Suarez‐Perez,Andrea Bonaccini Calia,Gaëlle Piret,Ramon Garcia-Cortadella,Xavi Illa,Elena Garcia,José Morales Sánchez,Damia Viana Casals,Elisabet Prats-Alfonso,Jessica Bousquet,Philippe Godignon,Blaise Yvert,Rosa Villa,Maria V. Sanchez-Vives,Anton Guimerà-Brunet,Jose A. Garrido +17 more
TLDR
In this article, the operation of solution-gated field-effect transistors (SGFETs) and characterizing their performance in saline solution were discussed and compared with the performance of state-of-the-art neural technologies.Abstract:
Brain–computer interfaces and neural prostheses based on the detection of electrocorticography (ECoG) signals are rapidly growing fields of research. Several technologies are currently competing to be the first to reach the market; however, none of them fulfill yet all the requirements of the ideal interface with neurons. Thanks to its biocompatibility, low dimensionality, mechanical flexibility, and electronic properties, graphene is one of the most promising material candidates for neural interfacing. After discussing the operation of graphene solution-gated field-effect transistors (SGFET) and characterizing their performance in saline solution, it is reported here that this technology is suitable for μ-ECoG recordings through studies of spontaneous slow-wave activity, sensory-evoked responses on the visual and auditory cortices, and synchronous activity in a rat model of epilepsy. An in-depth comparison of the signal-to-noise ratio of graphene SGFETs with that of platinum black electrodes confirms that graphene SGFET technology is approaching the performance of state-of-the art neural technologies.read more
Citations
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Journal ArticleDOI
Flexible Molybdenum Disulfide (MoS2) Atomic Layers for Wearable Electronics and Optoelectronics
TL;DR: The overall recent progress made in developing MoS2 based flexible FETs, OLED displays, nonvolatile memory (NVM) devices, piezoelectric nanogenerators (PNGs), and sensors for wearable electronic and optoelectronic devices is discussed.
Journal ArticleDOI
Graphene-based sensors for human health monitoring
TL;DR: Graphene-based sensors used for human health monitoring, their novel structures, sensing mechanisms, technological innovations, components for sensor systems and potential challenges will be discussed and outlined.
Journal ArticleDOI
Properties and behavior of carbon nanomaterials when interfacing neuronal cells: How far have we come?
TL;DR: In this paper, a review of carbon-based nanomaterials currently under investigation in basic and applied neuroscience, and the recent developments in this research field, with a special focus on in vitro studies.
Journal ArticleDOI
Single-layer graphene modulates neuronal communication and augments membrane ion currents
Niccolò Paolo Pampaloni,Martin Lottner,Michele Giugliano,Michele Giugliano,Alessia Matruglio,Francesco D'Amico,Maurizio Prato,Maurizio Prato,Jose A. Garrido,Laura Ballerini,Denis Scaini,Denis Scaini +11 more
TL;DR: It is shown that single-layer graphene increases neuronal firing by altering membrane-associated functions in cultured cells, and hypothesize that the graphene–ion interactions that are maximized when single- layer graphene is deposited on electrically insulating substrates are crucial to these effects.
Journal ArticleDOI
High-resolution mapping of infraslow cortical brain activity enabled by graphene microtransistors.
Eduard Masvidal-Codina,Xavi Illa,Miguel Dasilva,Andrea Bonaccini Calia,Tanja Dragojević,Ernesto E. Vidal-Rosas,Elisabet Prats-Alfonso,Javier Martínez-Aguilar,Jose Manuel de la Cruz,Ramon Garcia-Cortadella,Philippe Godignon,Gemma Rius,Alessandra Camassa,Elena del Corro,Jessica Bousquet,Clément Hébert,Turgut Durduran,Turgut Durduran,Rosa Villa,Maria V. Sanchez-Vives,Maria V. Sanchez-Vives,Jose A. Garrido,Jose A. Garrido,Anton Guimerà-Brunet +23 more
TL;DR: This work uses flexible epicortical and intracortical arrays of graphene solution-gated field-effect transistors (gSGFETs) to map cortical spreading depression in rats and demonstrates that gSGFETS are able to record, with high fidelity, infraslow signals together with signals in the typical local field potential bandwidth.
References
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Journal ArticleDOI
Roll-to-roll production of 30-inch graphene films for transparent electrodes
Sukang Bae,Hyeongkeun Kim,Youngbin Lee,Xiangfan Xu,Jaesung Park,Yi Zheng,Jayakumar Balakrishnan,Tian Lei,Hye Ri Kim,Young Il Song,Young Jin Kim,Kwang S. Kim,Barbaros Özyilmaz,Jong Hyun Ahn,Byung Hee Hong,Sumio Iijima,Sumio Iijima +16 more
TL;DR: The roll-to-roll production and wet-chemical doping of predominantly monolayer 30-inch graphene films grown by chemical vapour deposition onto flexible copper substrates are reported, showing high quality and sheet resistances superior to commercial transparent electrodes such as indium tin oxides.
Journal ArticleDOI
Deep brain stimulation for treatment-resistant depression.
Helen S. Mayberg,Helen S. Mayberg,Andres M. Lozano,Valerie Voon,Heather E. McNeely,David A. Seminowicz,Clement Hamani,Jason M. Schwalb,Sidney H. Kennedy +8 more
TL;DR: It is suggested that disrupting focal pathological activity in limbic-cortical circuits using electrical stimulation of the subgenual cingulate white matter can effectively reverse symptoms in otherwise treatment-resistant depression.
Journal ArticleDOI
One-dimensional electrical contact to a two-dimensional material.
Lei Wang,Inanc Meric,Pinshane Y. Huang,Qun Gao,Yuanda Gao,Helen Tran,Takashi Taniguchi,Kenji Watanabe,Luis M. Campos,David A. Muller,Jing Guo,Philip Kim,James Hone,Kenneth L. Shepard,Cory Dean,Cory Dean +15 more
TL;DR: In graphene heterostructures, the edge-contact geometry provides new design possibilities for multilayered structures of complimentary 2D materials, and enables high electronic performance, including low-temperature ballistic transport over distances longer than 15 micrometers, and room-tem temperature mobility comparable to the theoretical phonon-scattering limit.
Journal ArticleDOI
Development of an Ion-Sensitive Solid-State Device for Neurophysiological Measurements
TL;DR: The development of an ion-sensitive solid-state device that combines the principles of an MOS transistor and a glass electrode and can be used for measurements of ion activities in electrochemical and biological environments is described.
Journal ArticleDOI
Cortical control of a prosthetic arm for self-feeding
Meel Velliste,Sagi Perel,Sagi Perel,M. Chance Spalding,M. Chance Spalding,Andrew S. Whitford,Andrew S. Whitford,Andrew B. Schwartz +7 more
TL;DR: A system that permits embodied prosthetic control is described and monkeys (Macaca mulatta) use their motor cortical activity to control a mechanized arm replica in a self-feeding task, and this demonstration of multi-degree-of-freedom embodied prosthetics control paves the way towards the development of dexterous prosthetic devices that could ultimately achieve arm and hand function at a near-natural level.