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Journal ArticleDOI

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010.

TLDR
The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010) as discussed by the authors was used to estimate the burden of disease attributable to mental and substance use disorders in terms of disability-adjusted life years (DALYs), years of life lost to premature mortality (YLLs), and years lived with disability (YLDs).
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This article is published in The Lancet.The article was published on 2013-11-09. It has received 4753 citations till now. The article focuses on the topics: Years of potential life lost & Poison control.

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Pharmacogenomics in the treatment of mood disorders: Strategies and Opportunities for personalized psychiatry.

TL;DR: This review summarizes pharmacogenomic studies in mood disorders that may lay the foundation towards personalized psychiatry and suggests three alternative and complementary strategies to implement knowledge gained from pharmacogenome studies.
Journal ArticleDOI

Intrinsic functional connectivity predicts remission on antidepressants: a randomized controlled trial to identify clinically applicable imaging biomarkers

TL;DR: The findings demonstrate that the overall capacity to remit on commonly used antidepressants may depend on intact organization of intrinsic functional connectivity between PCC and ACC/mPFC prior to treatment, and highlight the potential utility of functional scans for advancing a more precise approach to tailoring antidepressant treatment choices.
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The Global Burden of Disease projects: what have we learned about illicit drug use and dependence and their contribution to the global burden of disease?

TL;DR: There is still much work to be done to generate defensible estimates of the magnitude of risk, particularly for impactful and prevalent outcomes, such as injuries, violence and mental health complications.
Journal ArticleDOI

Prevalence and factors associated with depression symptoms among school-going adolescents in Central Uganda.

TL;DR: Significant depression symptoms are prevalent among school-going adolescents and may progress to full-blown depressive disorders and Culturally sensitive psychological interventions to prevent and treat depression among school -going adolescents are urgently needed.
Journal ArticleDOI

The accuracy of passive phone sensors in predicting daily mood.

Abstract: Background Smartphones provide a low-cost and efficient means to collect population level data. Several small studies have shown promise in predicting mood variability from smartphone-based sensor and usage data, but have not been generalized to nationally recruited samples. This study used passive smartphone data, demographic characteristics, and baseline depressive symptoms to predict prospective daily mood. Method Daily phone usage data were collected passively from 271 Android phone users participating in a fully remote randomized controlled trial of depression treatment (BRIGHTEN). Participants completed daily Patient Health Questionnaire-2. A machine learning approach was used to predict daily mood for the entire sample and individual participants. Results Sample-wide estimates showed a marginally significant association between physical mobility and self-reported daily mood (B = -0.04, P 0.50) for 80.6% of participants and very strong prediction in a subset (median AUC > 0.80) for 11.8% of participants. Conclusions Passive smartphone data with current features may not be suited for predicting daily mood at a population level because of the high degree of intra- and interindividual variation in phone usage patterns and daily mood ratings. Personalized models show encouraging early signs for predicting an individual's mood state changes, with GPS-derived mobility being the top most important feature in the present sample.
References
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Journal ArticleDOI

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

TL;DR: Moher et al. as mentioned in this paper introduce PRISMA, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses, which is used in this paper.
Journal Article

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.

TL;DR: The QUOROM Statement (QUality Of Reporting Of Meta-analyses) as mentioned in this paper was developed to address the suboptimal reporting of systematic reviews and meta-analysis of randomized controlled trials.
Journal ArticleDOI

Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement

TL;DR: A structured summary is provided including, as applicable, background, objectives, data sources, study eligibility criteria, participants, interventions, study appraisal and synthesis methods, results, limitations, conclusions and implications of key findings.
Journal ArticleDOI

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, +195 more
- 15 Dec 2012 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.
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Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Christopher J L Murray, +369 more
- 15 Dec 2012 -