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Journal ArticleDOI

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010.

TLDR
The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010) as discussed by the authors was used to estimate the burden of disease attributable to mental and substance use disorders in terms of disability-adjusted life years (DALYs), years of life lost to premature mortality (YLLs), and years lived with disability (YLDs).
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This article is published in The Lancet.The article was published on 2013-11-09. It has received 4753 citations till now. The article focuses on the topics: Years of potential life lost & Poison control.

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Citations
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Depression, Cytokine, and Cytokine by Treatment Interactions Modulate Gene Expression in Antipsychotic Naive First Episode Psychosis

TL;DR: Increased IL-6 levels may prime the expression of genes (AKT1, DICER1, DROSHA, and COMT) in response to risperidone, suggesting that cytokine and gene interactions may improve cell function profiles.
Journal ArticleDOI

Impact of physiological, pathological and environmental factors on the expression and activity of human cytochrome P450 2D6 and implications in precision medicine.

TL;DR: Genotypes are key determinants of interindividual variability in CYP2D6 expression and activity and post-translational modifications such as phosphorylation of CYP 2D6 Ser135 have been observed, but the functional impact is unknown.
Journal ArticleDOI

Major depressive disorder and suicide risk among adult outpatients at several general hospitals in a Chinese Han population.

TL;DR: This study provides valuable data about the risk factors and association of MDD and suicide risk in adult outpatients in Han Chinese, which allow better the employment of preventative measures.
Journal ArticleDOI

New drug candidates for depression – a nationwide population‐based study

TL;DR: To investigate whether continued use of non‐aspirin NSAID, low‐dose aspirin, high‐ dose aspirin, statins, allopurinol and angiotensin agents decreases the rate of incident depression using Danish nationwide population‐based registers, a large number of patients are surveyed.
Journal ArticleDOI

Distinct Accumbens Shell Output Pathways Promote versus Prevent Relapse to Alcohol Seeking.

TL;DR: It is shown that contextual control over relapse and abstinence is embedded within distinct output circuits of dopamine 1 receptor (Drd1) expressing AcbSh neurons, which may reduce propensity to relapse to, and promote abstinence from, drug use.
References
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Journal ArticleDOI

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

TL;DR: Moher et al. as mentioned in this paper introduce PRISMA, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses, which is used in this paper.
Journal Article

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.

TL;DR: The QUOROM Statement (QUality Of Reporting Of Meta-analyses) as mentioned in this paper was developed to address the suboptimal reporting of systematic reviews and meta-analysis of randomized controlled trials.
Journal ArticleDOI

Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement

TL;DR: A structured summary is provided including, as applicable, background, objectives, data sources, study eligibility criteria, participants, interventions, study appraisal and synthesis methods, results, limitations, conclusions and implications of key findings.
Journal ArticleDOI

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, +195 more
- 15 Dec 2012 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.
Related Papers (5)

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Christopher J L Murray, +369 more
- 15 Dec 2012 -