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Journal ArticleDOI

Global burden of disease attributable to mental and substance use disorders: findings from the Global Burden of Disease Study 2010.

TLDR
The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010) as discussed by the authors was used to estimate the burden of disease attributable to mental and substance use disorders in terms of disability-adjusted life years (DALYs), years of life lost to premature mortality (YLLs), and years lived with disability (YLDs).
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This article is published in The Lancet.The article was published on 2013-11-09. It has received 4753 citations till now. The article focuses on the topics: Years of potential life lost & Poison control.

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Citations
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Brain Age in Early Stages of Bipolar Disorders or Schizophrenia.

TL;DR: Early stages of schizophrenia, but not early stages of BD, were associated with advanced BrainAGE scores, which could aid in early differential diagnosis between BD and schizophrenia.
Journal ArticleDOI

Microglial Over-Activation by Social Defeat Stress Contributes to Anxiety- and Depressive-Like Behaviors.

TL;DR: Evidence is highlighted for the negative impact of the over-activation of the neuroimmune system, especially by the overproduction of pro-inflammatory mediators and cytotoxins, that ultimately contribute to the development of anxiety- and depressive-like states.
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The Inflamed Brain in Schizophrenia: The Convergence of Genetic and Environmental Risk Factors That Lead to Uncontrolled Neuroinflammation.

TL;DR: The genetic risk factors for schizophrenia that modulate immune function are provided and the diverse roles that microglia play in response to neuroinflammation and their impact on brain development and homeostasis are described, as well as schizophrenia pathophysiology.
Journal ArticleDOI

Cortical thickness predicts the first onset of major depression in adolescence.

TL;DR: Findings indicate that cortical gray matter structure can predict the subsequent onset of depression, and an important direction for future research is to elucidate mechanisms by which these anomalies ingray matter structure increase risk for developing this disorder.
References
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Journal ArticleDOI

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement

TL;DR: Moher et al. as mentioned in this paper introduce PRISMA, an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses, which is used in this paper.
Journal Article

Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.

TL;DR: The QUOROM Statement (QUality Of Reporting Of Meta-analyses) as mentioned in this paper was developed to address the suboptimal reporting of systematic reviews and meta-analysis of randomized controlled trials.
Journal ArticleDOI

Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement

TL;DR: A structured summary is provided including, as applicable, background, objectives, data sources, study eligibility criteria, participants, interventions, study appraisal and synthesis methods, results, limitations, conclusions and implications of key findings.
Journal ArticleDOI

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, +195 more
- 15 Dec 2012 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.
Related Papers (5)

Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Christopher J L Murray, +369 more
- 15 Dec 2012 -