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Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary

TLDR
The assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation, and the concept of de‐escalation of therapy is introduced in the treatment assessment scheme.
Abstract
This Executive Summary of the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 Report focuses primarily on the revised and novel parts of the document. The most significant changes include: (i) the assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation. ABCD groups are now proposed to be derived exclusively from patient symptoms and their history of exacerbations; (ii) for each of the groups A to D, escalation strategies for pharmacological treatments are proposed; (iii) the concept of de-escalation of therapy is introduced in the treatment assessment scheme; (iv)non-pharmacological therapies are comprehensively presented and (v) the importance of co-morbid conditions in managing COPD is reviewed.

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Citations
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Dysregulated circulating microRNA‐126 in chronic obstructive pulmonary disease: linkage with acute exacerbation risk, severity degree, and inflammatory cytokines

TL;DR: The study aimed to evaluate the value of miR‐126 for estimating COPD acute exacerbation risk and its relation to disease severity and inflammatory cytokines in COPD patients.
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Dissecting Survival Pathways in Lung Cancer, Fibrosis and Emphysema: "The Four Horses of the Apocalypse".

TL;DR: Lung cancer patients with CPFE represent an increasingly recognized specific entity with extremely poor prognosis and limited therapeutic options, and prognosis becomes more complicated and unpredictable in patients with idiopathic pulmonary fibro.
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Muscle function and functional performance after pulmonary rehabilitation in patients with chronic obstructive pulmonary disease: a prospective observational study

TL;DR: In this article , the authors measured changes in different properties of skeletal muscles and evaluated their contribution and relationship to changes in functional performance after pulmonary rehabilitation (PR) in patients with chronic obstructive pulmonary disease (COPD).
Journal ArticleDOI

Chronisch obstruktive Lungenerkrankung und Komorbiditäten

B. Waschki, +1 more
- 21 Jul 2017 - 
TL;DR: An early diagnosis and consistent treatment are presumably the key to favorably influence the morbidity and mortality, particularly for cardiovascular comorbidities.
Journal ArticleDOI

Physical Activity Decline: The Challenge of Living Normal and Independent in COPD Patients

TL;DR: Findings indicated that the patterns of physical activities, communication, and self-care in COPD patients change toward living normal and independent.
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The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease

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Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease.

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Journal ArticleDOI

A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire.

TL;DR: The St. George's Respiratory Questionnaire is a valid measure of impaired health in diseases of chronic airflow limitation that is repeatable and sensitive andMultivariate analysis demonstrated that SGRQ scores summed a number of areas of disease activity.
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