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Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary

TLDR
The assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation, and the concept of de‐escalation of therapy is introduced in the treatment assessment scheme.
Abstract
This Executive Summary of the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 Report focuses primarily on the revised and novel parts of the document. The most significant changes include: (i) the assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation. ABCD groups are now proposed to be derived exclusively from patient symptoms and their history of exacerbations; (ii) for each of the groups A to D, escalation strategies for pharmacological treatments are proposed; (iii) the concept of de-escalation of therapy is introduced in the treatment assessment scheme; (iv)non-pharmacological therapies are comprehensively presented and (v) the importance of co-morbid conditions in managing COPD is reviewed.

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Citations
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Effects and safety of metformin in patients with concurrent diabetes mellitus and chronic obstructive pulmonary disease: a systematic review and meta-analysis

TL;DR: Metformin use is associated with lower risk of COPD-related hospitalizations and risk of all-cause mortality without increasing the risk of hyperlactatemia, and should be given to conduct more high-quality randomized trials involving larger samples.
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Proton Pump Inhibitor Treatment Improves Pulmonary Function in Acute Exacerbations of COPD Patients with 24‐hour Dx‐pH Monitoring‐diagnosed Laryngopharyngeal Reflux

TL;DR: In this paper, the frequency of laryngopharyngeal reflux (LPR)-related symptom incidence among acute exacerbations of COPD patients with Reflux Symptom Index (RSI) ≥ 13 and investigate proton pump inhibitor (PPI) treatment effect on LPR, COPD symptoms, and pulmonary function.
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A comparison of tiotropium/olodaterol vs tiotropium alone in terms of treatment effect for chronic obstructive pulmonary disease: A meta-analysis.

TL;DR: It was reported that the TIO/OLO combination did not show superior effects than tiotropium alone for COPD, and both therapies were well tolerated.
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Cough Assessment and Management in Pulmonary Rehabilitation- A Canadian Survey.

TL;DR: In this paper , a cross-sectional study was conducted to determine if and how chronic cough is assessed and managed in pulmonary rehabilitation programs in Canada, and a representative from each program was invited to complete an online survey including the following topics: program demographics, assessment and management practices, and barriers and facilitators.
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Implementation of the chronic obstructive pulmonary disease Assessment Test in clinical practice.

TL;DR: Implementation and utilization of COPD assessment tools, like the CAT, are practical and sustainable in a specialty practice setting and moreover, the CAT helps with COPD symptom management.
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A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire.

TL;DR: The St. George's Respiratory Questionnaire is a valid measure of impaired health in diseases of chronic airflow limitation that is repeatable and sensitive andMultivariate analysis demonstrated that SGRQ scores summed a number of areas of disease activity.
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