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Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary

TLDR
The assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation, and the concept of de‐escalation of therapy is introduced in the treatment assessment scheme.
Abstract
This Executive Summary of the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 Report focuses primarily on the revised and novel parts of the document. The most significant changes include: (i) the assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation. ABCD groups are now proposed to be derived exclusively from patient symptoms and their history of exacerbations; (ii) for each of the groups A to D, escalation strategies for pharmacological treatments are proposed; (iii) the concept of de-escalation of therapy is introduced in the treatment assessment scheme; (iv)non-pharmacological therapies are comprehensively presented and (v) the importance of co-morbid conditions in managing COPD is reviewed.

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Citations
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Behaviour change and physical activity interventions for physical activity engagement in community dwelling adults with chronic obstructive pulmonary disease: protocol for a systematic review

TL;DR: A systematic review of behaviour change and physical activity interventions delivered to community dwelling adults with COPD with the aim of increasing physical activity engagement is necessary to explain the impact of behaviour changes andPhysical activity interventions on outcomes of community dwelling people with COPd.
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Relationship between concavity of the flow-volume loop and small airway measures in smokers with normal spirometry

TL;DR: In this article , the authors evaluated concavity measures compared to known small airway measurements and found abnormal peripheral and global concavities as well as acinar ventilation heterogeneity are common in "normal" smokers.
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Machine learning for nocturnal diagnosis of chronic obstructive pulmonary disease using digital oximetry biomarkers

TL;DR: The results motivate that overnight single channel oximetry can be a valuable modality for COPD diagnosis, in a population sample at risk of sleep-disordered breathing.
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Clinical Efficacy of Carbocysteine in COPD: Beyond the Mucolytic Action

TL;DR: This analysis demonstrates that the use of carbocysteine in COPD patients represents a well-tolerated treatment with a favorable safety profile, and might contribute to a better quality of life for patients suffering from this serious illness.
Journal ArticleDOI

The association of chronic bronchitis and airflow obstruction with lifetime and current farm activities in a sample of rural adults in Iowa

TL;DR: It is suggested that work with crop storage insecticides or turkeys may increase the risk for chronic bronchitis and work in hog or chicken confinement may increaseThe risk for airflow obstruction.
References
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The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease

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Journal ArticleDOI

Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease.

TL;DR: The reduction in death from all causes among patients with COPD in the combination-therapy group did not reach the predetermined level of statistical significance, and there were significant benefits in all other outcomes among these patients.
Journal ArticleDOI

A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire.

TL;DR: The St. George's Respiratory Questionnaire is a valid measure of impaired health in diseases of chronic airflow limitation that is repeatable and sensitive andMultivariate analysis demonstrated that SGRQ scores summed a number of areas of disease activity.
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