Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary
Claus Vogelmeier,Gerard J. Criner,Fernando J. Martinez,Antonio Anzueto,Peter J. Barnes,Jean Bourbeau,Bartolome R. Celli,Rongchang Chen,Marc Decramer,Leonardo M. Fabbri,Peter Frith,David M.G. Halpin,M. Victorina López Varela,Masaharu Nishimura,Nicolas Roche,Roberto Rodriguez-Roisin,Don D. Sin,Dave Singh,Robert Stockley,Jørgen Vestbo,Jadwiga A. Wedzicha,Alvar Agusti +21 more
TLDR
The assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation, and the concept of de‐escalation of therapy is introduced in the treatment assessment scheme.Abstract:
This Executive Summary of the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 Report focuses primarily on the revised and novel parts of the document. The most significant changes include: (i) the assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation. ABCD groups are now proposed to be derived exclusively from patient symptoms and their history of exacerbations; (ii) for each of the groups A to D, escalation strategies for pharmacological treatments are proposed; (iii) the concept of de-escalation of therapy is introduced in the treatment assessment scheme; (iv)non-pharmacological therapies are comprehensively presented and (v) the importance of co-morbid conditions in managing COPD is reviewed.read more
Citations
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Association of Systemic Inflammation with Depressive Symptoms in Individuals with COPD.
Hilary C Strollo,Seyed Mehdi Nouraie,Karin F. Hoth,Craig M Riley,C. Karoleski,Yingze Zhang,Nicola A. Hanania,Russell P. Bowler,Jessica Bon,Frank C. Sciurba +9 more
TL;DR: In this article, the authors found that elevated plasma IL-6 levels are associated with depressive symptoms in individuals with COPD, independent of airflow limitation and comorbid risk factors for depression.
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Patricia Leutz-Schmidt,Patricia Leutz-Schmidt,Mark O. Wielpütz,Stephan Skornitzke,Oliver Weinheimer,Oliver Weinheimer,Hans-Ulrich Kauczor,Hans-Ulrich Kauczor,Michael Puderbach,Gregor Pahn,W Stiller,W Stiller,W Stiller +12 more
TL;DR: Densitometry is influenced by acquisition parameters and reconstruction algorithms to a degree that may be clinically negligible, however, in longitudinal studies and clinical research identical protocols and potentially other measures for calibration may be required.
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A Co-Designed Active Video Game for Physical Activity Promotion in People With Chronic Obstructive Pulmonary Disease: Pilot Trial
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Predicting severe chronic obstructive pulmonary disease exacerbations using quantitative CT: a retrospective model development and external validation study
Muhammad Faizyab Ali Chaudhary,Eric P. Hoffman,Jun-xiong Guo,Alejandro P. Comellas,John Newell,Prashant Nagpal,Spyridon Fortis,Gary E. Christensen,Sarah E. Gerard,Yue Pan,Di Wang,Fereidoun Abtin,Igor Barjaktarevic,R. Graham Barr,Surya P. Bhatt,Sandeep Bodduluri,Christopher B. Cooper,Lisa Gravens-Mueller,MeiLan K. Han,Ella A. Kazerooni,Fernando J. Martinez,Martha Menchaca,Victor E. Ortega,Robert Paine Iii,Joyce D. Schroeder,Prescott G. Woodruff,Joseph M. Reinhardt +26 more
TL;DR: In this article , the authors developed and validated quantitative CT-based models for predicting severe chronic obstructive pulmonary disease (COPD) exacerbations using 3-year follow-up data.
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Relative Contributions of Family History and a Polygenic Risk Score on COPD and Related Outcomes: COPDGene and ECLIPSE studies
Matthew Moll,Sharon M. Lutz,Auyon J. Ghosh,Phuwanat Sakornsalkolpat,Craig P. Hersh,Terri H. Beaty,Frank Dudbridge,Martin D. Tobin,Murray A. Mittleman,Edwin K. Silverman,Brian D. Hobbs,Michael H. Cho +11 more
TL;DR: Family history and the PRS provide complementary information for predicting COPD and related outcomes and future studies can address the impact of obtaining both measures in clinical practice.
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