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Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary

TLDR
The assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation, and the concept of de‐escalation of therapy is introduced in the treatment assessment scheme.
Abstract
This Executive Summary of the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 Report focuses primarily on the revised and novel parts of the document. The most significant changes include: (i) the assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation. ABCD groups are now proposed to be derived exclusively from patient symptoms and their history of exacerbations; (ii) for each of the groups A to D, escalation strategies for pharmacological treatments are proposed; (iii) the concept of de-escalation of therapy is introduced in the treatment assessment scheme; (iv)non-pharmacological therapies are comprehensively presented and (v) the importance of co-morbid conditions in managing COPD is reviewed.

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Citations
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Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles

TL;DR: The advantages of various drug delivery vehicles are discussed for better understanding of their utility in terms of current medical needs and the application of a wide range of nanomedicines is also described in the context of major chronic diseases.
Journal ArticleDOI

COPD Guidelines: A Review of the 2018 GOLD Report.

TL;DR: The salient features of the GOLD 2018 document are reviewed and commentary on features that merit further discussion are provided based on clinical experience and practice as well as literature review current as of February 2018.
Journal ArticleDOI

Chronic obstructive pulmonary disease in China: a nationwide prevalence study

TL;DR: The estimated overall prevalence of COPD in China in 2014–15 was 13·6%, indicating that this disease has become a major public-health problem.
References
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Journal ArticleDOI

Physician perceptions and management of COPD

Steven Kesten, +1 more
- 01 Jul 1993 - 
TL;DR: Primary care practitioners have a low index of suspicion for obstructive airway disease, markedly underutilized spirometry as a screening tool, consider beta 2-agonists first-line therapy for COPD and asthma, and despite considering COPDand asthma different disease processes, choose similar medications for each disorder.
Journal ArticleDOI

Long-acting beta-agonists in the management of chronic obstructive pulmonary disease: current and future agents

TL;DR: Once-daily LABAs used both alone and in combination with long-acting muscarinic antagonists represent a promising advance in the treatment of COPD, and are likely to further improve outcomes for patients.
Journal ArticleDOI

Mortality prediction in chronic obstructive pulmonary disease comparing the GOLD 2007 and 2011 staging systems: a pooled analysis of individual patient data

TL;DR: Neither GOLD COPD classification schemes have sufficient discriminatory power to be used clinically for risk classification at the individual level to predict total mortality for 3 years of follow-up and onwards, and the prognostic accuracy of the staging documents for mortality is compared.
Journal ArticleDOI

Pneumonia Risk with Inhaled Fluticasone Furoate and Vilanterol Compared with Vilanterol Alone in Patients with COPD

TL;DR: Radiographically confirmed pneumonia risk is increased with inhaled FF/VI, although at less than investigator-defined rates, and modifiable pneumonia risk factors should be considered when attempting to optimize COPD management.
Journal ArticleDOI

Radiographic Emphysema Predicts Low Bone Mineral Density in a Tobacco-exposed Cohort

TL;DR: Radiographic emphysema is a strong, independent predictor of low BMD in current and former smokers, and suggests a common mechanistic link between empysema and osteopenia/osteoporosis.
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