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Open AccessJournal ArticleDOI

Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary

TLDR
The assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation, and the concept of de‐escalation of therapy is introduced in the treatment assessment scheme.
Abstract
This Executive Summary of the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 Report focuses primarily on the revised and novel parts of the document. The most significant changes include: (i) the assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation. ABCD groups are now proposed to be derived exclusively from patient symptoms and their history of exacerbations; (ii) for each of the groups A to D, escalation strategies for pharmacological treatments are proposed; (iii) the concept of de-escalation of therapy is introduced in the treatment assessment scheme; (iv)non-pharmacological therapies are comprehensively presented and (v) the importance of co-morbid conditions in managing COPD is reviewed.

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Citations
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Journal ArticleDOI

COPD and Depression Analysis in Regard to Obstructive Pulmonary Levels

TL;DR: In this article , the effects of antidepressant therapy in patients with COPD and a depressive disorder in relation to COPD levels were assessed using descriptive statistics and analysis of variance, and the results showed a different distribution of depressive symptoms at a different stage of COPD.
Proceedings ArticleDOI

Experimental optimization of the exposure allocation for xenon-enhanced dual-energy x-ray imaging of lung function

TL;DR: In this paper , the authors investigated the optimal exposure allocation for XeDE X-ray imaging of lung function by experiment and to validate the predictions of their theoretical model using a custom-built chest phantom representing an adult female chest.
Journal ArticleDOI

Effect of Family Nutrition Therapy on Elderly Patients with Chronic Obstructive Pulmonary Disease

TL;DR: Oral enteral nutrition can improve the nutritional status, lung function, activity tolerance and quality of life of elderly patients with COPD in stable stage and malnutrition.
Journal ArticleDOI

Recent Advances (2015–2020) in Drug Discovery for Attenuation of Pulmonary Fibrosis and COPD

TL;DR: In this article , the authors made an attempt to summarize the recent studies on the effects of various chemical drugs that attenuate PF and increase patients' quality of life, based on the nature of the drug molecules, e.g., natural/biomoleculebased, synthetic-molecule-based PF inhibitors, etc.
References
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TL;DR: Screening with the use of low-dose CT reduces mortality from lung cancer, as compared with the radiography group, and the rate of death from any cause was reduced.
Journal ArticleDOI

The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease

TL;DR: The BODE index, a simple multidimensional grading system, is better than the FEV1 at predicting the risk of death from any cause and from respiratory causes among patients with COPD.
Journal ArticleDOI

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TL;DR: The reduction in death from all causes among patients with COPD in the combination-therapy group did not reach the predetermined level of statistical significance, and there were significant benefits in all other outcomes among these patients.
Journal ArticleDOI

A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire.

TL;DR: The St. George's Respiratory Questionnaire is a valid measure of impaired health in diseases of chronic airflow limitation that is repeatable and sensitive andMultivariate analysis demonstrated that SGRQ scores summed a number of areas of disease activity.
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