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Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary

TLDR
The assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation, and the concept of de‐escalation of therapy is introduced in the treatment assessment scheme.
Abstract
This Executive Summary of the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 Report focuses primarily on the revised and novel parts of the document. The most significant changes include: (i) the assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation. ABCD groups are now proposed to be derived exclusively from patient symptoms and their history of exacerbations; (ii) for each of the groups A to D, escalation strategies for pharmacological treatments are proposed; (iii) the concept of de-escalation of therapy is introduced in the treatment assessment scheme; (iv)non-pharmacological therapies are comprehensively presented and (v) the importance of co-morbid conditions in managing COPD is reviewed.

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Citations
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Correlation between serum IL-32 concentration and clinical parameters of stable COPD: a retrospective clinical analysis.

TL;DR: Investigating the association between serum interleukin 32 (IL-32) concentration and clinical parameters in patients with stable chronic obstructive pulmonary disease suggested that IL-32 may be a molecular biomarker that reflects the severity of COPD and contributes to the disease diagnosis.
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Peitu Shengjin Recipe Attenuates Airway Inflammation via the TLR4/NF-kB Signaling Pathway on Chronic Obstructive Pulmonary Disease

TL;DR: It is suggested that PSR and Biostime Probiotic Powder have protective effects on COPD rats, which may be achieved by modulating the TLR4/NF-kB signaling pathway.
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Contemporary Concise Review 2019: Chronic obstructive pulmonary disease

TL;DR: Patients with persistent hypercapnia may benefit from using NIMV during exercise testing and pulmonary rehabilitation and demand-activated oxygen delivery devices may be just as effective as continuous oxygen therapy in preventing significant oxyhaemoglobin desaturations in COPD patients.
Proceedings ArticleDOI

HealMA: a model-driven framework for automatic generation of IoT-based Android health monitoring applications

TL;DR: In this paper , the authors proposed a framework based on model-driven engineering that accelerates the development of IoT-based Android health monitoring mobile applications using traditional software development methods, which is called HealMA.
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Arterial stiffness in symptomatic smokers with normal lung function

TL;DR: The current investigation shows that the cardiovascular risk occurs in smokers with respiratory symptoms in the absence of bronchial obstruction, and these findings need to be confirmed in larger populations in order to inform the design of intensive preventive programmes.
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Journal ArticleDOI

A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire.

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