Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary
Claus Vogelmeier,Gerard J. Criner,Fernando J. Martinez,Antonio Anzueto,Peter J. Barnes,Jean Bourbeau,Bartolome R. Celli,Rongchang Chen,Marc Decramer,Leonardo M. Fabbri,Peter Frith,David M.G. Halpin,M. Victorina López Varela,Masaharu Nishimura,Nicolas Roche,Roberto Rodriguez-Roisin,Don D. Sin,Dave Singh,Robert Stockley,Jørgen Vestbo,Jadwiga A. Wedzicha,Alvar Agusti +21 more
TLDR
The assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation, and the concept of de‐escalation of therapy is introduced in the treatment assessment scheme.Abstract:
This Executive Summary of the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 Report focuses primarily on the revised and novel parts of the document. The most significant changes include: (i) the assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation. ABCD groups are now proposed to be derived exclusively from patient symptoms and their history of exacerbations; (ii) for each of the groups A to D, escalation strategies for pharmacological treatments are proposed; (iii) the concept of de-escalation of therapy is introduced in the treatment assessment scheme; (iv)non-pharmacological therapies are comprehensively presented and (v) the importance of co-morbid conditions in managing COPD is reviewed.read more
Citations
More filters
Journal ArticleDOI
Airflow Obstruction and Cardio-metabolic Comorbidities.
Filip J.J. Triest,Michael Studnicka,Frits M.E. Franssen,William M. Vollmer,Bernd Lamprecht,Emiel F.M. Wouters,Peter Burney,Lowie E.G.W. Vanfleteren,Lowie E.G.W. Vanfleteren +8 more
TL;DR: The role of common risk factors in explaining the coexistence of cardio-metabolic comorbidities and COPD is emphasized, and the adjusted risk for diabetes is lower in subjects with airflow obstruction.
Journal ArticleDOI
Estimating mortality among inpatients with acute exacerbation of chronic obstructive pulmonary disease using registry data
Zhengcun Pei,Yixin Sun,Shengfeng Wang,Yahong Chen,Ting Yang,Kewu Huang,Yan Zhang,Yin Huang,Chen Wang,Siyan Zhan +9 more
TL;DR: The study aimed to investigate the demographic characteristics, clinical features, diagnoses, and treatments of hospitalized exacerbation COPD patients, as well as their disease prognoses and economic costs, and to estimate all-cause mortality during hospital stay, AECOPD recurrence within 1 month after discharge, all- Cause and cause-specific mortality, frequency of AECopd recurrence, lung function, life quality, healthcare costs in the study period, etc.
Journal ArticleDOI
Looking into the eye of patients with chronic obstructive pulmonary disease: an opportunity for better microvascular profiling of these complex patients.
Anouk W. Vaes,Martijn A. Spruit,Martijn A. Spruit,Jan Theunis,Nandu Goswami,Lowie E.G.W. Vanfleteren,Frits M.E. Franssen,Emiel F.M. Wouters,Patrick De Boever,Patrick De Boever +9 more
TL;DR: It was demonstrated that structural and functional microvascular changes were more common and severe in COPD patients as compared to non‐COPD controls, although few retinal investigations have been performed in patients with COPD.
Journal ArticleDOI
PRMT6 mediates inflammation via activation of the NF-κB/p65 pathway on a cigarette smoke extract-induced murine emphysema model.
TL;DR: The overexpressed PRMT6 could serve as an inflammation inhibitor, potentially through blocking the NF-κB/p65 pathway in the murine emphysema model.
Journal ArticleDOI
Computational modeling of lung deposition of inhaled particles in chronic obstructive pulmonary disease (COPD) patients: identification of gaps in knowledge and data.
Koustav Ganguly,Ulrika Carlander,Estella D. G. Garessus,Markus Fridén,Markus Fridén,Ulf Eriksson,Ulrika Tehler,Gunnar Johanson +7 more
TL;DR: The aim of this review is to evaluate the availability of the fundamental knowledge and data required for modeling particle deposition in a COPD lung departing from the existing healthy lung models.
References
More filters
Journal ArticleDOI
Reduced lung-cancer mortality with low-dose computed tomographic screening.
Denise R. Aberle,Amanda M. Adams,Christine D. Berg,William C. Black,Jonathan D. Clapp,Richard M. Fagerstrom,Ilana F. Gareen,Constantine Gatsonis,Pamela M. Marcus,JoRean D. Sicks +9 more
TL;DR: Screening with the use of low-dose CT reduces mortality from lung cancer, as compared with the radiography group, and the rate of death from any cause was reduced.
Journal ArticleDOI
Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS/ERS position paper
Bartolome R. Celli,William MacNee,Alvar Agusti,Antonio Anzueto,B. Berg,A. S. Buist,Peter M.A. Calverley,Niels H. Chavannes,T. Dillard,Bonnie F. Fahy,Alan M. Fein,John E. Heffner,Suzanne C. Lareau,Paula Meek,Fernando J. Martinez,Walter T. McNicholas,Jean W M Muris,E. Austegard,Romain Pauwels,S. I. Rennard,Adriano G. Rossi,NM Siafakas,B. Tiep,Jørgen Vestbo,E. F. M. Wouters,Richard ZuWallack +25 more
TL;DR: The main goals of the updated document are to improve the quality of care provided to patients with COPD and to develop the project using a disease-oriented approach.
Journal ArticleDOI
The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease
Bartolome R. Celli,Claudia Cote,Jose M. Marin,Ciro Casanova,Maria Montes de Oca,Reina A. Mendez,Victor Pinto Plata,Howard Cabral +7 more
TL;DR: The BODE index, a simple multidimensional grading system, is better than the FEV1 at predicting the risk of death from any cause and from respiratory causes among patients with COPD.
Journal ArticleDOI
Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease.
Julie A. Anderson,Bartolome R. Celli,Gary T. Ferguson,Christine Jenkins,Paul W. Jones,Julie C. Yates,Jørgen Vestbo +6 more
TL;DR: The reduction in death from all causes among patients with COPD in the combination-therapy group did not reach the predetermined level of statistical significance, and there were significant benefits in all other outcomes among these patients.
Journal ArticleDOI
A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire.
TL;DR: The St. George's Respiratory Questionnaire is a valid measure of impaired health in diseases of chronic airflow limitation that is repeatable and sensitive andMultivariate analysis demonstrated that SGRQ scores summed a number of areas of disease activity.
Related Papers (5)
Standardisation of spirometry
Martin R. Miller,John L. Hankinson,Vito Brusasco,Felip Burgos,Richard Casaburi,Allan L. Coates,Robert O. Crapo,Paul L. Enright,C.P.M. van der Grinten,P. Gustafsson,R. Jensen,D.C. Johnson,Neil R. MacIntyre,Roy T. McKay,Daniel Navajas,O. F. Pedersen,Riccardo Pellegrino,Giovanni Viegi,J. Wanger +18 more
An official American thoracic society/European respiratory society statement: Key concepts and advances in pulmonary rehabilitation
Martijn A. Spruit,Sally J Singh,Chris Garvey,Richard ZuWallack,Linda Nici,Anne E Holland,Suzanne C. Lareau,Fabio Pitta,Louise Sewell,Jo Raskin,Jean Bourbeau,Rebecca Crouch,Frits M.E. Franssen,Richard Casaburi,Jan H. Vercoulen,Ioannis Vogiatzis,Rik Gosselink,Enrico Clini,Tanja Effing,Job van der Palen,Thierry Troosters,Daisy J.A. Janssen,Eileen G. Collins,Judith Garcia-Aymerich,Dina Brooks,Bonnie Fahy,Milo A. Puhan,Martine Hoogendoorn,Rachel Garrod,Annemie M. W. J. Schols,Brian W. Carlin,Roberto P. Benzo,Mike Morgan,Andrew L. Ries,Roger S. Goldstein,Claire A. Dowson,Jan Brozek,Claudio F. Donner,Emiel F.M. Wouters +38 more