Global Strategy for the Diagnosis, Management and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary
Claus Vogelmeier,Gerard J. Criner,Fernando J. Martinez,Antonio Anzueto,Peter J. Barnes,Jean Bourbeau,Bartolome R. Celli,Rongchang Chen,Marc Decramer,Leonardo M. Fabbri,Peter Frith,David M.G. Halpin,M. Victorina López Varela,Masaharu Nishimura,Nicolas Roche,Roberto Rodriguez-Roisin,Don D. Sin,Dave Singh,Robert Stockley,Jørgen Vestbo,Jadwiga A. Wedzicha,Alvar Agusti +21 more
TLDR
The assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation, and the concept of de‐escalation of therapy is introduced in the treatment assessment scheme.Abstract:
This Executive Summary of the Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 Report focuses primarily on the revised and novel parts of the document. The most significant changes include: (i) the assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation. ABCD groups are now proposed to be derived exclusively from patient symptoms and their history of exacerbations; (ii) for each of the groups A to D, escalation strategies for pharmacological treatments are proposed; (iii) the concept of de-escalation of therapy is introduced in the treatment assessment scheme; (iv)non-pharmacological therapies are comprehensively presented and (v) the importance of co-morbid conditions in managing COPD is reviewed.read more
Citations
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Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease: the GOLD science committee report 2019.
Dave Singh,Alvar Agusti,Antonio Anzueto,Peter J. Barnes,Jean Bourbeau,Bartolome R. Celli,Gerard J. Criner,Peter Frith,David M.G. Halpin,MeiLan K. Han,M. Victorina López Varela,Fernando J. Martinez,Maria Montes de Oca,Alberto Papi,Ian D. Pavord,Nicolas Roche,Don D. Sin,Robert A. Stockley,Jørgen Vestbo,Jadwiga A. Wedzicha,Claus Vogelmeier +20 more
TL;DR: Blood eosinophils are recommended as a biomarker to support clinical decisions regarding the use of inhaled corticosteroids in chronic obstructive pulmonary disease patients, based on recent evidence from clinical trials.
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Targeted therapy in chronic diseases using nanomaterial-based drug delivery vehicles
TL;DR: The advantages of various drug delivery vehicles are discussed for better understanding of their utility in terms of current medical needs and the application of a wide range of nanomedicines is also described in the context of major chronic diseases.
Journal ArticleDOI
COPD Guidelines: A Review of the 2018 GOLD Report.
TL;DR: The salient features of the GOLD 2018 document are reviewed and commentary on features that merit further discussion are provided based on clinical experience and practice as well as literature review current as of February 2018.
Journal ArticleDOI
Chronic obstructive pulmonary disease in China: a nationwide prevalence study
Liwen Fang,Pei Gao,H L Bao,Xun Tang,Baohua Wang,Yajing Feng,S Cong,Juan Juan,J Fan,Ke Lu,Ning Wang,Yonghua Hu,Linhong Wang +12 more
TL;DR: The estimated overall prevalence of COPD in China in 2014–15 was 13·6%, indicating that this disease has become a major public-health problem.
References
More filters
Journal ArticleDOI
Pulmonary arterial enlargement and acute exacerbations of COPD.
J. Michael Wells,George R. Washko,MeiLan K. Han,Naseer Abbas,Hrudaya Nath,A. James Mamary,Elizabeth A. Regan,William C. Bailey,Fernando J. Martinez,Elizabeth Westfall,Terri H. Beaty,Douglas Curran-Everett,Jeffrey L. Curtis,Jeffrey L. Curtis,John E. Hokanson,David A. Lynch,Barry J. Make,James D. Crapo,Edwin K. Silverman,Russell P. Bowler,Mark T. Dransfield,Mark T. Dransfield +21 more
TL;DR: In this article, a multivariate logistic-regression analysis showed a significant association between a PA:A ratio of more than 1 and a history of severe exacerbations at the time of enrollment in the trial (odds ratio, 4.78; 95% confidence interval [CI], 3.43 to 6.65; P 1).
Journal ArticleDOI
Endobronchial Valves for Emphysema without Interlobar Collateral Ventilation
Karin Klooster,Nick H. T. ten Hacken,Jorine E. Hartman,Huib A. M. Kerstjens,Eva M. van Rikxoort,Dirk-Jan Slebos +5 more
TL;DR: Endobronchial-valve treatment significantly improved pulmonary function and exercise capacity in patients with severe emphysema characterized by an absence of interlobar collateral ventilation.
Journal ArticleDOI
A Randomized Controlled Trial of Cold-Adapted and Inactivated Vaccines for the Prevention of Influenza A Disease
Kathryn M. Edwards,William D. Dupont,Mary K. Westrich,Walton D. Plummer,Pamela Palmer,Peter F. Wright +5 more
TL;DR: Cold-adapted and inactivated influenza vaccines are safe and effective for preventing influenza A disease and significantly increased hemagglutination inhibition antibody titers.
Journal Article
Tiotropium in Combination with Placebo, Salmeterol, or Fluticasone–Salmeterol for Treatment of Chronic Obstructive Pulmonary Disease
Shawn D. Aaron,Katherine L. Vandemheen,Dean Fergusson,Jean Bourbeau,Roger S. Goldstein,Meyer Balter,Andrew McIvor,Sat Sharma,Graham Bishop,John Anthony,Robert L. Cowie,Stephen K. Field,Andrew Hirsch,Paul Hernandez,R. N. Rivington,Jeremy Road,Victor Hoffstein,Richard V. Hodder,Darcy D. Marciniuk,David G. McCormack,George A Fox,Gerard Cox,Henry B. Prins,Gordon T. Ford,Dominique Bleskie,Steve Doucette,Irvin Mayers,Kenneth R. Chapman,Noe Zamel,Mark FitzGerald +29 more
TL;DR: In this article, the combination of inhaled corticosteroids and long-acting β-agonists and anticholinergic bronchodilators for chronic obstructive pulmonary disease (COPD) was investigated.
Journal ArticleDOI
Influenza vaccine for patients with chronic obstructive pulmonary disease
TL;DR: It appears, from the limited number of studies performed, that inactivated vaccine may reduce exacerbations in COPD patients, and was due to a reduction in exacerbations occurring three or more weeks after vaccination.
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