Journal ArticleDOI
Golden age of insecticide research: past, present, or future?
John E. Casida,Gary B. Quistad +1 more
TLDR
Insecticide research, having passed through several Golden Ages, is now in a renaissance of integrating chemicals and biologicals for sustainable pest control with human safety.Abstract:
Insecticide research led to the first "complete" victories in combatting pests almost 50 years ago with the chlorinated hydrocarbons followed quickly by the organophosphates, methylcarbamates, and pyrethroids--all neuroactive chemicals. This Golden Age of Discovery was the source of most of our current insecticides. The challenge then became health and the environment, a Golden Age met with selective and degradable compounds. Next the focus shifted to resistance, novel biochemical targets, and new chemical approaches for pest control. The current Golden Age of Genetic Engineering has curtailed, but is unlikely to eliminate, chemical use on major crops. Insecticide research, having passed through several Golden Ages, is now in a renaissance of integrating chemicals and biologicals for sustainable pest control with human safety.read more
Citations
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Journal ArticleDOI
Benzophenyl urea insecticides – useful and eco-friendly options for insect pest control
TL;DR: The aim of this review is to gather comprehensive information about benzophenyl urea insecticide related to its development, mode of action, bioefficacy, environmental fate and ecotoxicity, which may be helpful for the researchers for future endeavour.
Journal ArticleDOI
Toxicity of Six Insecticides on Codling Moth (Lepidoptera: Tortricidae) and Effect on Expression of Detoxification Genes
TL;DR: Results suggest that the reduced-risk biorational insecticide acetamiprid is an effective insecticide with no induction of detoxification genes and can be integrated into the management of codling moth.
Journal Article
Vulnerability of different life stages of Bactrocera zonata (Tephritidae: Diptera) against entomogenous fungi.
TL;DR: Results showed higher adult mortality in contact bioassay for all the fungi tested as compared to the other methods of application, and symptoms of dark, shrinked pupae, deformed adults and incomplete adult emergence from the pupae were also observed after immature treatments with insect pathogenic fungi.
Journal ArticleDOI
Structural Studies on Vertebrate and Invertebrate Acetylcholinesterases and Their Complexes With Functional Ligands
TL;DR: The structure of Torpedo californica acetylcholinesterase (AChE) was examined in complex with several inhibitors which are either in use or under development for treatment of Alzheimer's disease.
Book ChapterDOI
Insect Pest Resistance: An Alternative Approach for Crop Protection
Md. Aslam Khan,Zehra Khan,Wasim Ahmad,Bishwajeet Paul,Sangeeta Paul,Chetana Aggarwal,Mohd Sayeed Akhtar +6 more
TL;DR: Biological control is a component of integrated pest management strategies that minimize insecticide spray applications and move towards ecofriendly systems of pest management.
References
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Book ChapterDOI
Safer and more effective insecticides for the future
John E. Casida,Gary B. Quistad +1 more
TL;DR: The use of synthetic organic insecticides has served for the past half century as the principal means to control insect-borne diseases and minimize losses in food and fibre production from pest insect attack as mentioned in this paper.
Related Papers (5)
NEONICOTINOID INSECTICIDE TOXICOLOGY: Mechanisms of Selective Action
Motohiro Tomizawa,John E. Casida +1 more