Journal ArticleDOI
Golden age of insecticide research: past, present, or future?
John E. Casida,Gary B. Quistad +1 more
TLDR
Insecticide research, having passed through several Golden Ages, is now in a renaissance of integrating chemicals and biologicals for sustainable pest control with human safety.Abstract:
Insecticide research led to the first "complete" victories in combatting pests almost 50 years ago with the chlorinated hydrocarbons followed quickly by the organophosphates, methylcarbamates, and pyrethroids--all neuroactive chemicals. This Golden Age of Discovery was the source of most of our current insecticides. The challenge then became health and the environment, a Golden Age met with selective and degradable compounds. Next the focus shifted to resistance, novel biochemical targets, and new chemical approaches for pest control. The current Golden Age of Genetic Engineering has curtailed, but is unlikely to eliminate, chemical use on major crops. Insecticide research, having passed through several Golden Ages, is now in a renaissance of integrating chemicals and biologicals for sustainable pest control with human safety.read more
Citations
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Journal ArticleDOI
Rapid determination of the synthetic pyrethroid insecticide, deltamethrin, in rat plasma and tissues by HPLC
TL;DR: A more rapid and sensitive high-performance liquid chromatography (HPLC) method to analyze DLM in plasma and tissues (liver, kidney, and brain) was developed and validated and was shown to be selective for DLM and linear over the concentration range 0.01-20.0 microg/ml.
Book ChapterDOI
Neonicotinoid insecticides: historical evolution and resistance mechanisms.
TL;DR: A number of derivatives and analogues ofimidacloprid have been generated to date, one of which has a characteristic tetrahydro-3-furylmethyl group instead of the pyridine-like rings of others neonicotinoids.
Journal ArticleDOI
The association between environmental exposure to pyrethroids and sperm aneuploidy.
Michał Radwan,Joanna Jurewicz,Bartosz Wielgomas,Marta Piskunowicz,Wojciech Sobala,Paweł Radwan,Lucjusz Jakubowski,Wanda Hawuła,Wojciech Hanke +8 more
TL;DR: It is found that pyrethroids may be a sperm aneugens and may be of concern due to increased pyrethroid use and prevalent human exposure.
Journal ArticleDOI
Coactivity of sulfide ingredients: a new perspective of the larvicidal activity of garlic essential oil against mosquitoes.
TL;DR: The addition of DDS to EO did not change the toxic effect of the essential oil, whereas the presence of DS in excess produced an enriched essential oil with low toxicity.
Book ChapterDOI
Management of Bemisia tabaci Whiteflies
TL;DR: Adopting IPM will alleviate the numerous concerns that accompany the use of chemicals, including those associated with environmental pollution and the widespread resistance that plagues B. tabaci management.
References
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Book ChapterDOI
Safer and more effective insecticides for the future
John E. Casida,Gary B. Quistad +1 more
TL;DR: The use of synthetic organic insecticides has served for the past half century as the principal means to control insect-borne diseases and minimize losses in food and fibre production from pest insect attack as mentioned in this paper.
Related Papers (5)
NEONICOTINOID INSECTICIDE TOXICOLOGY: Mechanisms of Selective Action
Motohiro Tomizawa,John E. Casida +1 more