Journal ArticleDOI
Golden age of insecticide research: past, present, or future?
John E. Casida,Gary B. Quistad +1 more
TLDR
Insecticide research, having passed through several Golden Ages, is now in a renaissance of integrating chemicals and biologicals for sustainable pest control with human safety.Abstract:
Insecticide research led to the first "complete" victories in combatting pests almost 50 years ago with the chlorinated hydrocarbons followed quickly by the organophosphates, methylcarbamates, and pyrethroids--all neuroactive chemicals. This Golden Age of Discovery was the source of most of our current insecticides. The challenge then became health and the environment, a Golden Age met with selective and degradable compounds. Next the focus shifted to resistance, novel biochemical targets, and new chemical approaches for pest control. The current Golden Age of Genetic Engineering has curtailed, but is unlikely to eliminate, chemical use on major crops. Insecticide research, having passed through several Golden Ages, is now in a renaissance of integrating chemicals and biologicals for sustainable pest control with human safety.read more
Citations
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Journal ArticleDOI
The progressive alteration of urine metabolomic profiles of rats following long-term and low-dose exposure to permethrin.
TL;DR: The time-course alteration of metabolomic profiles of the urine based on 1H NMR reflects the progressive development of the chronic toxicity with the long-term low-level exposure of permethrin.
Journal ArticleDOI
Oral exposure of deltamethrin and/or lipopolysaccharide (LPS) induced activation of the pulmonary immune system in Swiss albino mice
TL;DR: Deltamethrin exposure alone and/or with endotoxin revealed different degrees of immunopositive reaction for Toll-like receptor 4 (TLR4) and pro-inflammatory cytokine-like tumor necrosis factor-alpha (TNFα) in different parts of the lungs.
Journal ArticleDOI
Adverse Effects of Sixty Days Sub-chronic Exposure to β-cyfluthrin on Male Rats
Journal ArticleDOI
Dominance of Asia II 1 species of Bemisia tabaci in Pakistan and beyond
Muhammad Arsalan Mahmood,Nasim Ahmad,S. R. S. Hussain,Sidratul Muntaha,Imran Amin,Shahid Mansoor +5 more
TL;DR: In this article , a comparative analysis of B. tabaci species in Asia where Asia II 1 has been reported was conducted and a total of 5142 B.tabaci sequences of mtCO1 from Asian countries were analyzed to determine the species and their distribution in the region.
References
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Book ChapterDOI
Safer and more effective insecticides for the future
John E. Casida,Gary B. Quistad +1 more
TL;DR: The use of synthetic organic insecticides has served for the past half century as the principal means to control insect-borne diseases and minimize losses in food and fibre production from pest insect attack as mentioned in this paper.
Related Papers (5)
NEONICOTINOID INSECTICIDE TOXICOLOGY: Mechanisms of Selective Action
Motohiro Tomizawa,John E. Casida +1 more