Journal ArticleDOI
Golden age of insecticide research: past, present, or future?
John E. Casida,Gary B. Quistad +1 more
TLDR
Insecticide research, having passed through several Golden Ages, is now in a renaissance of integrating chemicals and biologicals for sustainable pest control with human safety.Abstract:
Insecticide research led to the first "complete" victories in combatting pests almost 50 years ago with the chlorinated hydrocarbons followed quickly by the organophosphates, methylcarbamates, and pyrethroids--all neuroactive chemicals. This Golden Age of Discovery was the source of most of our current insecticides. The challenge then became health and the environment, a Golden Age met with selective and degradable compounds. Next the focus shifted to resistance, novel biochemical targets, and new chemical approaches for pest control. The current Golden Age of Genetic Engineering has curtailed, but is unlikely to eliminate, chemical use on major crops. Insecticide research, having passed through several Golden Ages, is now in a renaissance of integrating chemicals and biologicals for sustainable pest control with human safety.read more
Citations
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Journal ArticleDOI
Influence of bifentrin, a pyrethriod pesticide, on human colorectal HCT-116 cells attributed to alterations in oxidative stress involving mitochondrial apoptotic processes.
TL;DR: Data indicated that BIF-induced cytotoxicity in human colorectal HCT-116 cells was associated with oxidative stress, mitochondrial dysfunction, and apoptosis.
Dissertation
Synthesis, mosquito repellence and apoptotic activity of functionalized monoterpenes.
TL;DR: A Thesis Submitted in Fulfillment of the Requirement for the Degree of Doctor of Philosophy (Physics) as mentioned in this paper was submitted to the University of Coventry.
Journal ArticleDOI
Efficient polymer‐mediated delivery system for thiocyclam: Nanometerization remarkably improves the bioactivity toward green peach aphids
Ye Wang,Yong Xie,Qinhong Jiang,Hongtao Chen,Ruihao Ma,Zhi-jiang Wang,Meizhen Yin,Jie Shen,Shuo Yan +8 more
TL;DR: In this paper , a star polymer (SPc) was constructed as an efficient pesticide nanocarrier/adjuvant that could spontaneously assemble with thiocyclam or monosultap into a complex, through hydrophobic association and hydrogen bonding, respectively.
Journal ArticleDOI
Immune detection of acetylcholinesterase in subcellular compartments of Trypanosoma evansi.
TL;DR: Novel data is shown that help to understand the non-neuronal role of AChE in the Trypanosomatidae family that is not present in either the cytosol or the plasma membrane of T. evansi.
References
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Book ChapterDOI
Safer and more effective insecticides for the future
John E. Casida,Gary B. Quistad +1 more
TL;DR: The use of synthetic organic insecticides has served for the past half century as the principal means to control insect-borne diseases and minimize losses in food and fibre production from pest insect attack as mentioned in this paper.
Related Papers (5)
NEONICOTINOID INSECTICIDE TOXICOLOGY: Mechanisms of Selective Action
Motohiro Tomizawa,John E. Casida +1 more