Journal ArticleDOI
Golden age of insecticide research: past, present, or future?
John E. Casida,Gary B. Quistad +1 more
TLDR
Insecticide research, having passed through several Golden Ages, is now in a renaissance of integrating chemicals and biologicals for sustainable pest control with human safety.Abstract:
Insecticide research led to the first "complete" victories in combatting pests almost 50 years ago with the chlorinated hydrocarbons followed quickly by the organophosphates, methylcarbamates, and pyrethroids--all neuroactive chemicals. This Golden Age of Discovery was the source of most of our current insecticides. The challenge then became health and the environment, a Golden Age met with selective and degradable compounds. Next the focus shifted to resistance, novel biochemical targets, and new chemical approaches for pest control. The current Golden Age of Genetic Engineering has curtailed, but is unlikely to eliminate, chemical use on major crops. Insecticide research, having passed through several Golden Ages, is now in a renaissance of integrating chemicals and biologicals for sustainable pest control with human safety.read more
Citations
More filters
Journal ArticleDOI
Larvicidal Activity of Inorganic Salts Against Anopheles Stephensi and Culex Quinquefasciatus
TL;DR: The present study showed that the inorganic salts Na2 CO3, NaHCO3, (NH4)2SO4 and NaH2PO4 could serve as potential larviciding agents considering their low toxicity.
Book ChapterDOI
Magic Bullets I, History, Philosophy and Criticisms
TL;DR: These investigations into the history, philosophy, and defects of the magic bullet strategy provide a framework for critically examining genetically engineered crops in terms of three categories: side effects, revenge effects, and balance between reductive and holistic strategies.
Book ChapterDOI
A good start lasts a lifetime: Endocrine-disrupting chemicals and their impact on embryonic and fetal development
DissertationDOI
Development of diagnostic tools for detecting expression of resistance-associated esterases in the tobacco budworm, Heliothis virescens (F.)
TL;DR: Esterase-based metabolic resistance was studied using biochemical and biological assays with organophosphate (OP)- and pyrethroid (PYR)-resistant tobacco budworms, Heliothis virescens as discussed by the authors .
Journal ArticleDOI
Síntesis de posibles agonistas nicotínicos con potencial actividad insecticida
TL;DR: The compuesto N-bencilpiridina-3-carboxaimidoato de etilo, N-(2-feniletil)piridinil-3 carboxaimidina 3 carboxamida as mentioned in this paper, was used as material de partida for obtener N-(3- aminopropil)-N-(2)-bencilnicotinamida, con buen rendimiento.
References
More filters
Book ChapterDOI
Safer and more effective insecticides for the future
John E. Casida,Gary B. Quistad +1 more
TL;DR: The use of synthetic organic insecticides has served for the past half century as the principal means to control insect-borne diseases and minimize losses in food and fibre production from pest insect attack as mentioned in this paper.
Related Papers (5)
NEONICOTINOID INSECTICIDE TOXICOLOGY: Mechanisms of Selective Action
Motohiro Tomizawa,John E. Casida +1 more