Journal ArticleDOI
Golden age of insecticide research: past, present, or future?
John E. Casida,Gary B. Quistad +1 more
TLDR
Insecticide research, having passed through several Golden Ages, is now in a renaissance of integrating chemicals and biologicals for sustainable pest control with human safety.Abstract:
Insecticide research led to the first "complete" victories in combatting pests almost 50 years ago with the chlorinated hydrocarbons followed quickly by the organophosphates, methylcarbamates, and pyrethroids--all neuroactive chemicals. This Golden Age of Discovery was the source of most of our current insecticides. The challenge then became health and the environment, a Golden Age met with selective and degradable compounds. Next the focus shifted to resistance, novel biochemical targets, and new chemical approaches for pest control. The current Golden Age of Genetic Engineering has curtailed, but is unlikely to eliminate, chemical use on major crops. Insecticide research, having passed through several Golden Ages, is now in a renaissance of integrating chemicals and biologicals for sustainable pest control with human safety.read more
Citations
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Journal ArticleDOI
Golden Age of RyR and GABA-R Diamide and Isoxazoline Insecticides: Common Genesis, Serendipity, Surprises, Selectivity, and Safety
TL;DR: The discovery of the insecticidal activity of a candidate herbicide was the first in a series of surprises that changed the course of insecticide research and opened the "Golden Age of Diamide and Isoxazoline Insecticides" which have a common genesis.
Journal ArticleDOI
Recent advances in hormones in insect pest control
TL;DR: The review presents information on novel insecticides that mimic the action of two insect growth and developmental hormone classes, the ecdysteroids and the juvenile hormones.
Journal Article
Mosquito larvicidal activity of aqueous extracts of long pepper (Piper retrofractum vahl) from Thailand.
Uruyakorn Chansang,Nayer S. Zahiri,Jaree Bansiddhi,Thidarat Boonruad,Pratom Thongsrirak,Jiranuch Mingmuang,Nipa Benjapong,Mir S. Mulla +7 more
TL;DR: Aqueous extracts of nine medicinal plants were bioassayed against larvae of Culex quinquefasciatus Say and Aedes aegypt (L.) and the long pepper, Piper retrofractum Vahl (Piperaceae), showed the highest level of activity against mosquito larvae.
Journal ArticleDOI
Impact of European legislation on marketed pesticides--a view from the standpoint of health impact assessment studies.
Anastasios J. Karabelas,Konstantinos V. Plakas,Ermioni Solomou,V. Drossou,Dimosthenis Sarigiannis +4 more
TL;DR: The very significant impact of European legislation on the authorization of plant protection products is reviewed, which has resulted in withdrawal of 704 active substances (AS) out of 889 assessed so far, and it is suggested that new HIA studies should focus on a rather short time frame and, therefore, on appropriate cohort groups, e.g. young children.
Journal ArticleDOI
Oxidative stress induced by lambda-cyhalothrin (LTC) in rat erythrocytes and brain: Attenuation by vitamin C
TL;DR: The results indicated the potential effects of LTC to induce oxidative damage in tissues and the ability of vitamin C to attenuate LTC-induced oxidative damage and its possible attenuation by vitamin C.
References
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Book ChapterDOI
Safer and more effective insecticides for the future
John E. Casida,Gary B. Quistad +1 more
TL;DR: The use of synthetic organic insecticides has served for the past half century as the principal means to control insect-borne diseases and minimize losses in food and fibre production from pest insect attack as mentioned in this paper.
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NEONICOTINOID INSECTICIDE TOXICOLOGY: Mechanisms of Selective Action
Motohiro Tomizawa,John E. Casida +1 more