Health benefits and health claims of probiotics: bridging science and marketing
Ger T. Rijkers,Willem M. de Vos,Robert-Jan M. Brummer,Lorenzo Morelli,Gérard Corthier,Philippe Marteau +5 more
TLDR
An open dialogue between basic and clinical scientists, regulatory authorities, food and nutrition industry, and consumers could bridge the gap between science and marketing of probiotics.Abstract:
Health claims for probiotics are evaluated by the Panel on Dietetic Products, Nutrition and Allergies of the European Food Safety Authority. Despite a substantial amount of basic and clinical research on the beneficial effects of probiotics, all of the evaluated claim applications thus far have received a negative opinion. With the restrictions on the use of clinical endpoints, validated biomarkers for gut health and immune health in relation to reduction in disease risk are needed. Clear-cut criteria for design as well as evaluation of future studies are needed. An open dialogue between basic and clinical scientists, regulatory authorities, food and nutrition industry, and consumers could bridge the gap between science and marketing of probiotics.read more
Citations
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Journal ArticleDOI
Novel perspectives on therapeutic modulation of the gut microbiota.
TL;DR: A pathophysiological overview of potential therapeutic applications of the gut microbiota is provided to indicate that certain bacteria can induce protective immune responses and enhance intestinal barrier function, which could be potential therapeutic targets.
Journal ArticleDOI
Whey and Its Derivatives for Probiotics, Prebiotics, Synbiotics, and Functional Foods: a Critical Review
Ourdia Kareb,Mohammed Aider +1 more
TL;DR: The purpose of this review is to highlight the importance of whey as a source of new-generation functional ingredients and the role of probiotics in the development of novel foods such as synbiotics.
Journal ArticleDOI
The gut microbiota as a key regulator of visceral pain.
TL;DR: Visceral pain can range from the discomfort of indigestion to the excruciating pain of renal colic, and is a major distinguishing feature in IBS patients.
Journal ArticleDOI
A meta-analysis of probiotic and synbiotic use in elective surgery: does nutrition modulation of the gut microbiome improve clinical outcome?
James Kinross,Sheraz R. Markar,Alan Karthikesalingam,Andre Chow,Nicholas Penney,David B.A. Silk,Ara Darzi +6 more
TL;DR: In this paper, a meta-analysis assessed the effect of probiotic and synbiotic preparations on the incidence of postoperative sepsis in patients undergoing elective general surgical procedures.
Journal ArticleDOI
The underexposed role of food matrices in probiotic products: Reviewing the relationship between carrier matrices and product parameters.
TL;DR: Results indicate that carrier matrices have a significant impact on the quality of probiotic products, and strain-dependent matrix effects on the GIT survival and clinical efficacy are shown.
References
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