Journal ArticleDOI
HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)
Chloe L. Thio,Eric C. Seaberg,Richard L. Skolasky,John P. Phair,Barbara R. Visscher,Alvaro Muñoz,David L. Thomas +6 more
TLDR
Individuals coinfected with HIV-1 and HBV, especially those with low CD4+ nadir counts, are at increased risk for liver-related mortality, underscoring the importance of prevention, identification, and comprehensive management of hepatitis B in people infected withAIDS.Citations
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A review on infection with human immunodeficiency virus.
TL;DR: Management of infection with human immunodeficiency virus (HIV) improved dramatically during the 1990s and better knowledge of the life cycle of HIV has made it possible to design new classes of antiretroviral drugs.
Journal ArticleDOI
Strategies for managing coinfection with hepatitis B virus and HIV.
TL;DR: Standard or pegylated interferon may be appropriate treatment for chronic HBV infection for patients who have not yet started highly active antiretroviral therapy (HAART) for their HIV.
Journal ArticleDOI
Coinfections with hepatitis B and C virus and syphilis among HIV-infected clients in Southern Ethiopia: a cross-sectional study.
Techalew Shimelis,Yayheyirad Tassachew,Agete Tadewos,Mesfin Worku Hordofa,Anteneh Amsalu,Birkneh Tilahun Tadesse,Endale Tadesse +6 more
TL;DR: The rates of HBV and HCV infections among HIV-infected patients at a tertiary hospital in Southern Ethiopia were found to be similar to other subpopulations in Ethiopia, with age and CD4+ T cell level influenced the rate ofHBV exposure.
Journal ArticleDOI
Higher prevalence of cancer related mutations 1762T/1764A and PreS deletions in hepatitis B virus (HBV) isolated from HBV/HIV co-infected compared to HBV-mono-infected Chinese adults
Kai-Wen Li,Anna Kramvis,Shujia Liang,Xiang He,Qin-Yan Chen,Chao Wang,Qing-Li Yang,Li-Ping Hu,Hui-Hua Jia,Zhong-Liao Fang +9 more
TL;DR: Co-infection with HIV was associated with increased prevalence of HCC-related HBV mutations in HBV isolates from Chinese patients, and multivariate analysis revealed that 1762T/1764A and preS deletions occurred more frequently in genotypes C and I compared to genotype B.
Journal ArticleDOI
Nevirapine-containing regimens in HIV-infected naive patients with CD4 cell counts of 200 cells/μl or less
Elena Ferrer,Elena Santamariña,Pere Domingo,Emilio Fumero,Esteban Ribera,Hernando Knobel,J. C. López,Ana Barrios,Daniel Podzamczer +8 more
TL;DR: It is found that naive patients initiating highly active antiretroviral therapy with CD4 cell counts S 200 cells/jl and after 24 months, 51% of patients continued nevirapine, and 83% had viral loads < 50 copies/ml by intent-to-treat and on-treatment analyses, and a mean increase of +246 CD4 cells/microl occurred.
References
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Journal Article
Statistical methods in cancer research. Volume II--The design and analysis of cohort studies.
N. E. Breslow,N. E. Day +1 more
TL;DR: What do you do to start reading statistical methods in cancer research vol ii the design and analysis of cohort studies?
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The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994
Miriam J. Alter,Deanna Kruszon-Moran,Omana V. Nainan,Geraldine M. McQuillan,Fengxiang Gao,Linda A. Moyer,Richard A. Kaslow,Harold S. Margolis +7 more
TL;DR: The strongest factors independently associated with HCV infection were illegal drug use and high-risk sexual behavior, and poverty, having had 12 or fewer years of education, and having been divorced or separated were independently associated.
Journal ArticleDOI
Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients
Yves Benhamou,Marie Bochet,V. Di Martino,Frédéric Charlotte,F. Azria,Anne Coutellier,Michel Vidaud,François Bricaire,Pierre Opolon,Christine Katlama,Thierry Poynard +10 more
TL;DR: In coinfected patients, a low CD4 count, alcohol consumption rate, and age at HCV infection are associated with a higher liver fibrosis progression rate, while HIV seropositivity accelerates HCV‐related liver Fibrosis progression.
Journal ArticleDOI
The multicenter aids cohort study: rationale, organization, and selected characteristics of the participants
TL;DR: The Multicenter AIDS Cohort Study was designed to elucidate the natural history of the infection causing acquired immunodeficiency syndrome (AIDS), identify risk factors for occurrence and clinical expression of the virus, and establish a repository of biologic specimens for future study.
Journal ArticleDOI
Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
TL;DR: The data indicate that use of ritonavir may increase risk of severe hepatotoxicity, and does not support withholding protease inhibitor therapy from persons coinfected with hepatitis B or C virus.