Journal ArticleDOI
HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)
Chloe L. Thio,Eric C. Seaberg,Richard L. Skolasky,John P. Phair,Barbara R. Visscher,Alvaro Muñoz,David L. Thomas +6 more
TLDR
Individuals coinfected with HIV-1 and HBV, especially those with low CD4+ nadir counts, are at increased risk for liver-related mortality, underscoring the importance of prevention, identification, and comprehensive management of hepatitis B in people infected withAIDS.Citations
More filters
Journal ArticleDOI
The prevalence liver function and immunologic status of children with hiv and hepatitis b virus coinfection in enugu, nigeria.
Uleanya Nwachinemere Davidson,Nwokoye Ikenna Chidiebele,Emodi Ifeoma Josephine,Obidike Egbuna Olakunle,Ikefuna Anthony Nnaemeka,Eze Jude Chijioke,Ndu Ikenna Kingsley +6 more
TL;DR: HBV co- Infection among HIV infected children is common in the authors' environment, and co-infection is associated with impaired immunity and probably liver enzyme derangement.
Journal ArticleDOI
Brief Report: Relationship Between ABCC4 SNPs and Hepatitis B Virus Suppression During Tenofovir-Containing Antiretroviral Therapy in Patients With HIV/HBV Coinfection.
Timothy N. Archampong,Oluwayemisi Ojewale,Kristi Bears,Yiqing Chen,Margaret Lartey,Kwamena W. Sagoe,Adjoa Obo-Akwa,Yan Gong,Taimour Y. Langaee,Awewura Kwara +9 more
TL;DR: A novel association between ABCC4 rs11568695 SNP and poor HBV treatment response is identified and could be used to identify individuals who may need intensified HBV therapy.
Journal ArticleDOI
Naturally occurring antiviral drug resistance in HIV patients who are mono-infected or co-infected with HBV or HCV in China
Haohui Deng,Haohui Deng,Xizi Deng,Yu Liu,Ying Xu,Yun Lan,Ming Gao,Min Xu,Hongbo Gao,Xiexing Wu,Baolin Liao,Weilie Chen,Miaoxian Zhao,Fengyu Hu,Zhanhui Wang +14 more
TL;DR: HBV DRMs were more prevalent in HIV/HBV co‐infected patients in China, while DRMs in HCV and HIV patients did not differ, and dynamic surveillance of DRMs may be needed.
Journal ArticleDOI
Upregulation of interleukin-27 expression is correlated with higher CD4+ T cell counts in treatment of naive human immunodeficiency virus-infected Chinese
TL;DR: The findings suggest that the elevated plasma IL-27 levels may play important role in slowing down the CD4+ T cell declining in HIV-infected individuals and the process of AIDS disease.
Journal ArticleDOI
Risk of liver-associated morbidity and mortality in a cohort of HIV and HBV coinfected Han Chinese
Rongrong Yang,Xien Gui,Yong Xiong,Shicheng Gao,Yongxi Zhang,Liping Deng,Ke Liang,Yajun Yan,Yu-ping Rong +8 more
TL;DR: Lamivudine-based cART was beneficial in terms of sustained HBV viral suppression and resulted in less incidence of ALDs, common among HIV and HBV coinfected Han Chinese patients.
References
More filters
Journal Article
Statistical methods in cancer research. Volume II--The design and analysis of cohort studies.
N. E. Breslow,N. E. Day +1 more
TL;DR: What do you do to start reading statistical methods in cancer research vol ii the design and analysis of cohort studies?
Journal ArticleDOI
The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994
Miriam J. Alter,Deanna Kruszon-Moran,Omana V. Nainan,Geraldine M. McQuillan,Fengxiang Gao,Linda A. Moyer,Richard A. Kaslow,Harold S. Margolis +7 more
TL;DR: The strongest factors independently associated with HCV infection were illegal drug use and high-risk sexual behavior, and poverty, having had 12 or fewer years of education, and having been divorced or separated were independently associated.
Journal ArticleDOI
Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients
Yves Benhamou,Marie Bochet,V. Di Martino,Frédéric Charlotte,F. Azria,Anne Coutellier,Michel Vidaud,François Bricaire,Pierre Opolon,Christine Katlama,Thierry Poynard +10 more
TL;DR: In coinfected patients, a low CD4 count, alcohol consumption rate, and age at HCV infection are associated with a higher liver fibrosis progression rate, while HIV seropositivity accelerates HCV‐related liver Fibrosis progression.
Journal ArticleDOI
The multicenter aids cohort study: rationale, organization, and selected characteristics of the participants
TL;DR: The Multicenter AIDS Cohort Study was designed to elucidate the natural history of the infection causing acquired immunodeficiency syndrome (AIDS), identify risk factors for occurrence and clinical expression of the virus, and establish a repository of biologic specimens for future study.
Journal ArticleDOI
Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
TL;DR: The data indicate that use of ritonavir may increase risk of severe hepatotoxicity, and does not support withholding protease inhibitor therapy from persons coinfected with hepatitis B or C virus.