Journal ArticleDOI
HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)
Chloe L. Thio,Eric C. Seaberg,Richard L. Skolasky,John P. Phair,Barbara R. Visscher,Alvaro Muñoz,David L. Thomas +6 more
TLDR
Individuals coinfected with HIV-1 and HBV, especially those with low CD4+ nadir counts, are at increased risk for liver-related mortality, underscoring the importance of prevention, identification, and comprehensive management of hepatitis B in people infected withAIDS.Citations
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Causes of Death and Risk Factors for Mortality among HIV-Infected Patients Receiving Antiretroviral Therapy in Korea
Sun Hee Lee,Kye-Hyung Kim,Seung-Geun Lee,Heerim Cho,Dong Hwan Chen,Joo Seop Chung,Ihm Soo Kwak,Goon Jae Cho +7 more
TL;DR: Different strategies to reduce mortality according to the time period after ART initiation are needed, as CD4 cell count ≤ 50 cells/µL at ART initiation, hepatitis B virus co-infection, and visit constancy ≤ 50% were significant risk factors for death.
Journal ArticleDOI
Prevalence and risk factors for chronic hepatitis B in HIV patients attended at a sexually-transmitted disease clinic in Vitoria, Brazil
Adriana Marchon Zago,Thayla Ferrari Machado,Flavia Lagrota Cazarim,Angélica Espinosa Miranda +3 more
TL;DR: Chronic HBV was associated with intravenous drug use, male gender, STI associated with HIV diagnosis, and death, and there is a need for prevention and assistance strategies to control the evolution of this infection in HIV patients.
Journal ArticleDOI
Solid organ transplantation is a reality for patients with HIV infection.
TL;DR: Because important patient selection and clinical management questions remain, it is critical that ongoing studies are completed quickly, and the implications are critical, as late referral for liver transplant evaluation increases the pretransplant mortality risk.
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Prevalence and associations with hepatitis B and hepatitis C infection among HIV-infected adults in South Africa.
Christopher J. Hoffmann,Dinesh Dayal,Mireille Cheyip,James McIntyre,Glenda Gray,Shaun Conway,Neil A. Martinson,Neil A. Martinson +7 more
TL;DR: It was found that subjects with HBsAg positivity had lower CD4 counts, a moderate prevalence of bothHBsAg and anti-HBc, which is associated with alcohol use, traditional medicines and higherCD4 counts.
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Prognosis of patients with chronic hepatitis B in France (2008-2013): A nationwide, observational and hospital-based study.
TL;DR: In France, 2008–2013, liver disease progression among patients with chronic hepatitis B was closely related to other risk factors, and HIV co-infected patients without AIDS had better outcomes, suggesting better care in this group of patients.
References
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Journal Article
Statistical methods in cancer research. Volume II--The design and analysis of cohort studies.
N. E. Breslow,N. E. Day +1 more
TL;DR: What do you do to start reading statistical methods in cancer research vol ii the design and analysis of cohort studies?
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The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994
Miriam J. Alter,Deanna Kruszon-Moran,Omana V. Nainan,Geraldine M. McQuillan,Fengxiang Gao,Linda A. Moyer,Richard A. Kaslow,Harold S. Margolis +7 more
TL;DR: The strongest factors independently associated with HCV infection were illegal drug use and high-risk sexual behavior, and poverty, having had 12 or fewer years of education, and having been divorced or separated were independently associated.
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Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients
Yves Benhamou,Marie Bochet,V. Di Martino,Frédéric Charlotte,F. Azria,Anne Coutellier,Michel Vidaud,François Bricaire,Pierre Opolon,Christine Katlama,Thierry Poynard +10 more
TL;DR: In coinfected patients, a low CD4 count, alcohol consumption rate, and age at HCV infection are associated with a higher liver fibrosis progression rate, while HIV seropositivity accelerates HCV‐related liver Fibrosis progression.
Journal ArticleDOI
The multicenter aids cohort study: rationale, organization, and selected characteristics of the participants
TL;DR: The Multicenter AIDS Cohort Study was designed to elucidate the natural history of the infection causing acquired immunodeficiency syndrome (AIDS), identify risk factors for occurrence and clinical expression of the virus, and establish a repository of biologic specimens for future study.
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Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
TL;DR: The data indicate that use of ritonavir may increase risk of severe hepatotoxicity, and does not support withholding protease inhibitor therapy from persons coinfected with hepatitis B or C virus.