Journal ArticleDOI
HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)
Chloe L. Thio,Eric C. Seaberg,Richard L. Skolasky,John P. Phair,Barbara R. Visscher,Alvaro Muñoz,David L. Thomas +6 more
TLDR
Individuals coinfected with HIV-1 and HBV, especially those with low CD4+ nadir counts, are at increased risk for liver-related mortality, underscoring the importance of prevention, identification, and comprehensive management of hepatitis B in people infected withAIDS.Citations
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Proficiency of transient elastography compared to liver biopsy for the assessment of fibrosis in HIV/HBV-coinfected patients.
Patrick Miailhes,Patrick Miailhes,Pierre Pradat,Pierre Pradat,M. Chevallier,Karine Lacombe,François Bailly,François Bailly,Laurent Cotte,Laurent Cotte,Mary-Anne Trabaud,André Boibieux,J. Bottero,C. Trepo,C. Trepo,Fabien Zoulim,Fabien Zoulim +16 more
TL;DR: In HIV/HBV‐coinfected patients, most of them with normal ALT under antiretroviral treatment including HBV active drugs, TE was proficient in discriminating moderate to severe fibrosis from minimal liver disease.
Journal ArticleDOI
Hepatitis B virus infection among people attending the voluntary counselling and testing centre and anti-retroviral therapy clinic of St Paul's General Specialised Hospital, Addis Ababa, Ethiopia.
Techalew Shimelis,Workineh Torben,Girmaye Medhin,Mekashaw Tebeje,Anteneh Andualm,Fekadu Demessie,Andargachew Mulu,Belete Tegbaru,Solomon Gebre-Selassie +8 more
TL;DR: This study shows a high prevalence and similar distribution of HBV infection in HIV-positive and HIV-negative people, however, with the emphasis given to HIV- positive cases, screening forHBV infection is important.
Journal ArticleDOI
Problem of hepatocellular carcinoma in West Africa.
Nimzing G. Ladep,Olufunmilayo A. Lesi,Pantong Mark,Maud Lemoine,Charles Onyekwere,Mary Afihene,Mary M.E. Crossey,Simon D. Taylor-Robinson +7 more
TL;DR: Highlighted reasons for the specific disease pattern of HCC in West Africa include: high rate of risk factors; failure to identify at risk populations; lack of effective treatment; and scarce resources for timely diagnosis.
Journal ArticleDOI
Low rates of hepatitis screening and vaccination of HIV-infected MSM in HIV clinics.
Karen W. Hoover,Mary Butler,Kimberly A. Workowski,Stephen Follansbee,Beau Gratzer,C. Bradley Hare,Barbara Johnston,John L. Theodore,Guoyu Tao,Bryce D. Smith,Terence Chorba,Charlotte K. Kent +11 more
TL;DR: Despite recommendations for hepatitis screening and vaccination of HIV-infected MSM, rates were suboptimal at all clinic sites, highlighting the importance of routine review of adherence to recommended clinical services.
Journal ArticleDOI
Vaccination in HIV-infected adults
TL;DR: A review of the current recommendations regarding vaccines among HIV-infected adults and a comprehensive summary of the evidence-based literature of the benefits and risks of vaccines among this vulnerable population are provided.
References
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Journal Article
Statistical methods in cancer research. Volume II--The design and analysis of cohort studies.
N. E. Breslow,N. E. Day +1 more
TL;DR: What do you do to start reading statistical methods in cancer research vol ii the design and analysis of cohort studies?
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The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994
Miriam J. Alter,Deanna Kruszon-Moran,Omana V. Nainan,Geraldine M. McQuillan,Fengxiang Gao,Linda A. Moyer,Richard A. Kaslow,Harold S. Margolis +7 more
TL;DR: The strongest factors independently associated with HCV infection were illegal drug use and high-risk sexual behavior, and poverty, having had 12 or fewer years of education, and having been divorced or separated were independently associated.
Journal ArticleDOI
Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients
Yves Benhamou,Marie Bochet,V. Di Martino,Frédéric Charlotte,F. Azria,Anne Coutellier,Michel Vidaud,François Bricaire,Pierre Opolon,Christine Katlama,Thierry Poynard +10 more
TL;DR: In coinfected patients, a low CD4 count, alcohol consumption rate, and age at HCV infection are associated with a higher liver fibrosis progression rate, while HIV seropositivity accelerates HCV‐related liver Fibrosis progression.
Journal ArticleDOI
The multicenter aids cohort study: rationale, organization, and selected characteristics of the participants
TL;DR: The Multicenter AIDS Cohort Study was designed to elucidate the natural history of the infection causing acquired immunodeficiency syndrome (AIDS), identify risk factors for occurrence and clinical expression of the virus, and establish a repository of biologic specimens for future study.
Journal ArticleDOI
Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
TL;DR: The data indicate that use of ritonavir may increase risk of severe hepatotoxicity, and does not support withholding protease inhibitor therapy from persons coinfected with hepatitis B or C virus.