Journal ArticleDOI
HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)
Chloe L. Thio,Eric C. Seaberg,Richard L. Skolasky,John P. Phair,Barbara R. Visscher,Alvaro Muñoz,David L. Thomas +6 more
TLDR
Individuals coinfected with HIV-1 and HBV, especially those with low CD4+ nadir counts, are at increased risk for liver-related mortality, underscoring the importance of prevention, identification, and comprehensive management of hepatitis B in people infected withAIDS.Citations
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Chronic hepatitis B: integrating long-term treatment data and strategies to improve outcomes in clinical practice.
TL;DR: This monograph will review recently published data on hepatitis B antiviral medications, as well as explore when to consider cessation of therapy, the treatment of special patient populations and the need to screen patients for hepatocellular carcinoma.
Journal ArticleDOI
Response to hepatitis B vaccination among HIV-infected adults in Vietnam.
Todd M. Pollack,Le Thi Thu Trang,Long Ngo,Long Ngo,Do Duy Cuong,Pham Thanh Thuy,Donn J Colby +6 more
TL;DR: It is found that the CD4 T cell count at the time of vaccination to be the sole predictor of response to HBV vaccination among HIV-infected Vietnamese adults, highlighting the importance of vaccinating HIV- infected adults prior to advanced immunosuppression.
Journal ArticleDOI
Hepatitis B virus and HIV coinfection among adults residing in Cameroon: A systematic review and meta-analysis of prevalence studies
TL;DR: Although the prevalence of HIV-HBV coinfection in Cameroon was found to be a low, this study presented a high HBV prevalence in people with HIV, indicating effective strategies to interrupt the transmission of HBV are required.
Journal ArticleDOI
Epidemiological and clinical characteristics of hepatitis B virus in HIV-infected patients in Guangdong, China.
TL;DR: The level of CD4 cell count in HIV/HBV co-infected patients was much lower than HIV mono- Infected patients, especially in patients who were HBeAg-positive and had a high level of HBV-DNA.
Journal ArticleDOI
HIV Co-Infection with Hepatotropic Viruses and Mycobacterial Tuberculosis
TL;DR: In this paper, a descriptive review of co-infection in HIV positive individuals is presented, which shows that HIV coinfection accelerates the natural course of hepatotropic viruses and increased risk of liver cirrhosis, hepatocellular carcinoma, and decompensated liver disease in coinfected individuals.
References
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Statistical methods in cancer research. Volume II--The design and analysis of cohort studies.
N. E. Breslow,N. E. Day +1 more
TL;DR: What do you do to start reading statistical methods in cancer research vol ii the design and analysis of cohort studies?
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The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994
Miriam J. Alter,Deanna Kruszon-Moran,Omana V. Nainan,Geraldine M. McQuillan,Fengxiang Gao,Linda A. Moyer,Richard A. Kaslow,Harold S. Margolis +7 more
TL;DR: The strongest factors independently associated with HCV infection were illegal drug use and high-risk sexual behavior, and poverty, having had 12 or fewer years of education, and having been divorced or separated were independently associated.
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Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients
Yves Benhamou,Marie Bochet,V. Di Martino,Frédéric Charlotte,F. Azria,Anne Coutellier,Michel Vidaud,François Bricaire,Pierre Opolon,Christine Katlama,Thierry Poynard +10 more
TL;DR: In coinfected patients, a low CD4 count, alcohol consumption rate, and age at HCV infection are associated with a higher liver fibrosis progression rate, while HIV seropositivity accelerates HCV‐related liver Fibrosis progression.
Journal ArticleDOI
The multicenter aids cohort study: rationale, organization, and selected characteristics of the participants
TL;DR: The Multicenter AIDS Cohort Study was designed to elucidate the natural history of the infection causing acquired immunodeficiency syndrome (AIDS), identify risk factors for occurrence and clinical expression of the virus, and establish a repository of biologic specimens for future study.
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Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
TL;DR: The data indicate that use of ritonavir may increase risk of severe hepatotoxicity, and does not support withholding protease inhibitor therapy from persons coinfected with hepatitis B or C virus.