Journal ArticleDOI
HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)
Chloe L. Thio,Eric C. Seaberg,Richard L. Skolasky,John P. Phair,Barbara R. Visscher,Alvaro Muñoz,David L. Thomas +6 more
TLDR
Individuals coinfected with HIV-1 and HBV, especially those with low CD4+ nadir counts, are at increased risk for liver-related mortality, underscoring the importance of prevention, identification, and comprehensive management of hepatitis B in people infected withAIDS.Citations
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Prevalence and virological profiles of hepatitis B infection in human immunodeficiency virus patients.
Koffi Alain Attia,Serge Eholié,Eugène Messou,Christine Danel,Sandrine Polneau,Henri Chenal,Thomas d'Aquin Toni,Myreille Mbamy,Catherine Seyler,Naomi Wakasugi,Thérèse N'Dri-Yoman,Xavier Anglaret +11 more
TL;DR: HBV infection prevalence is high in HIV-positive patients, and HBeAg positive chronic hepatitis and occult HBV infection are more frequent in HIV -positive patients than in HIV negative ones.
Journal ArticleDOI
Hepatitis B or hepatitis C and human immunodeficiency virus infection
Journal ArticleDOI
Factors associated with seroconversion after standard dose hepatitis B vaccination and high-dose revaccination among HIV-infected patients.
TL;DR: HDR appears to be a viable strategy to achieve seroconversion among HIV-infected patients who fail to respond to SDV, and higher CD4 at vaccination, younger age, and receipt of Twinrix were independently associated with SDVSeroconversion.
Journal ArticleDOI
Dually Active HIV/HBV Antiretrovirals as Protection Against Incident Hepatitis B Infections: Potential for Prophylaxis.
Mohaned Shilaih,Alex Marzel,Alexandra U. Scherrer,Dominique L Braun,Helen Kovari,Mathieu Rougemont,Katharine E A Darling,Manuel Battegay,Matthias Hoffmann,Enos Bernasconi,Cédric Hirzel,Huldrych F. Günthard,Roger D. Kouyos +12 more
TL;DR: The study suggests that DAART, independently of CD4 cell count and risky behavior, has a potentially strong public health impact, including pre-exposure prophylaxis of HBV coinfection in the HIV infected.
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Documento de consenso de la AEEH sobre el tratamiento de la infección por el virus de la hepatitis B (2012)
Maria Buti,Javier García-Samaniego,Martín Prieto,Manuel Rodríguez,José María Sánchez-Tapias,E. Suárez,Rafael Esteban +6 more
TL;DR: The treatment of choice is the long-term administration of a nucleos(t)ide analogue with high barrier to resistance (entecavir, tenofovir or ten ofovir alafenamide).
References
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Journal Article
Statistical methods in cancer research. Volume II--The design and analysis of cohort studies.
N. E. Breslow,N. E. Day +1 more
TL;DR: What do you do to start reading statistical methods in cancer research vol ii the design and analysis of cohort studies?
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The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994
Miriam J. Alter,Deanna Kruszon-Moran,Omana V. Nainan,Geraldine M. McQuillan,Fengxiang Gao,Linda A. Moyer,Richard A. Kaslow,Harold S. Margolis +7 more
TL;DR: The strongest factors independently associated with HCV infection were illegal drug use and high-risk sexual behavior, and poverty, having had 12 or fewer years of education, and having been divorced or separated were independently associated.
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Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients
Yves Benhamou,Marie Bochet,V. Di Martino,Frédéric Charlotte,F. Azria,Anne Coutellier,Michel Vidaud,François Bricaire,Pierre Opolon,Christine Katlama,Thierry Poynard +10 more
TL;DR: In coinfected patients, a low CD4 count, alcohol consumption rate, and age at HCV infection are associated with a higher liver fibrosis progression rate, while HIV seropositivity accelerates HCV‐related liver Fibrosis progression.
Journal ArticleDOI
The multicenter aids cohort study: rationale, organization, and selected characteristics of the participants
TL;DR: The Multicenter AIDS Cohort Study was designed to elucidate the natural history of the infection causing acquired immunodeficiency syndrome (AIDS), identify risk factors for occurrence and clinical expression of the virus, and establish a repository of biologic specimens for future study.
Journal ArticleDOI
Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
TL;DR: The data indicate that use of ritonavir may increase risk of severe hepatotoxicity, and does not support withholding protease inhibitor therapy from persons coinfected with hepatitis B or C virus.