Journal ArticleDOI
HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)
Chloe L. Thio,Eric C. Seaberg,Richard L. Skolasky,John P. Phair,Barbara R. Visscher,Alvaro Muñoz,David L. Thomas +6 more
TLDR
Individuals coinfected with HIV-1 and HBV, especially those with low CD4+ nadir counts, are at increased risk for liver-related mortality, underscoring the importance of prevention, identification, and comprehensive management of hepatitis B in people infected withAIDS.Citations
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Studies on Prevalence, Co-Infection and Associated Risk Factors of Hepatitis B Virus (HBV) and Human Immunodeficiency Virus (HIV) in Benue State, Nigeria
TL;DR: The Benue State of Nigeria is one of the regions in sub-Saharan Africa facing rising morbidity and mortality, among adult individuals, from HIV/AIDS and other sexually transmitted diseases and there is need to upgrade the status of medical facilities especially in rural hospitals as well as the personnel towards safer blood transfusions.
Journal ArticleDOI
HIV, Aging, and Viral Coinfections: Taking the Long View.
TL;DR: An understanding of how viral suppression alters the natural history of HIV infection is developed, especially at the intersection of HIV with other common viral coinfections in the context of an altered, aging immune system is developed.
Journal ArticleDOI
Diagnosis and management of cirrhosis in coinfected patients
TL;DR: Liver transplantation is feasible in patients with HIV infection, and early evaluation for this option is crucial because of the accelerated course of complications in HIV coinfection, where survival is shorter in coinfected patients.
Journal ArticleDOI
Association between Syphilis, Antibodies to Herpes Simplex Virus Type 2, and Recreational Drug Use and Hepatitis B Virus Infection in the Women's Interagency HIV Study
Phyllis C. Tien,Phyllis C. Tien,Andrea Kovacs,Peter Bacchetti,Audrey L. French,Michael Augenbraun,Stephen R. Cole,Nancy A. Hessol,Jessica E. Justman +8 more
TL;DR: A high prevalence of HBV infection was found in a cohort of women with and at risk for HIV infection and HSV-2 seropositivity and a history of syphilis appeared to be important correlates ofHBV infection.
Journal ArticleDOI
Hyaluronic acid levels predict increased risk of non-AIDS death in hepatitis-coinfected persons interrupting antiretroviral therapy in the SMART Study.
Lars Peters,Jacqueline Neuhaus,Amanda Mocroft,Vincent Soriano,Jürgen K. Rockstroh,Gregory J. Dore,Massimo Puoti,Ellen Tedaldi,Bonaventura Clotet,Bernd Kupfer,Jens D Lundgren,Marina B. Klein +11 more
TL;DR: Interruption of ART was particularly unsafe in HIV-hepatitis-coinfected individuals if plasma HA was increased and was not influenced by differences in CD4(+) T-cell count or HIV viral load.
References
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Journal Article
Statistical methods in cancer research. Volume II--The design and analysis of cohort studies.
N. E. Breslow,N. E. Day +1 more
TL;DR: What do you do to start reading statistical methods in cancer research vol ii the design and analysis of cohort studies?
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The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994
Miriam J. Alter,Deanna Kruszon-Moran,Omana V. Nainan,Geraldine M. McQuillan,Fengxiang Gao,Linda A. Moyer,Richard A. Kaslow,Harold S. Margolis +7 more
TL;DR: The strongest factors independently associated with HCV infection were illegal drug use and high-risk sexual behavior, and poverty, having had 12 or fewer years of education, and having been divorced or separated were independently associated.
Journal ArticleDOI
Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients
Yves Benhamou,Marie Bochet,V. Di Martino,Frédéric Charlotte,F. Azria,Anne Coutellier,Michel Vidaud,François Bricaire,Pierre Opolon,Christine Katlama,Thierry Poynard +10 more
TL;DR: In coinfected patients, a low CD4 count, alcohol consumption rate, and age at HCV infection are associated with a higher liver fibrosis progression rate, while HIV seropositivity accelerates HCV‐related liver Fibrosis progression.
Journal ArticleDOI
The multicenter aids cohort study: rationale, organization, and selected characteristics of the participants
TL;DR: The Multicenter AIDS Cohort Study was designed to elucidate the natural history of the infection causing acquired immunodeficiency syndrome (AIDS), identify risk factors for occurrence and clinical expression of the virus, and establish a repository of biologic specimens for future study.
Journal ArticleDOI
Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
TL;DR: The data indicate that use of ritonavir may increase risk of severe hepatotoxicity, and does not support withholding protease inhibitor therapy from persons coinfected with hepatitis B or C virus.