Journal ArticleDOI
HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)
Chloe L. Thio,Eric C. Seaberg,Richard L. Skolasky,John P. Phair,Barbara R. Visscher,Alvaro Muñoz,David L. Thomas +6 more
TLDR
Individuals coinfected with HIV-1 and HBV, especially those with low CD4+ nadir counts, are at increased risk for liver-related mortality, underscoring the importance of prevention, identification, and comprehensive management of hepatitis B in people infected withAIDS.Citations
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Dynamics of plasma hepatitis B virus levels after highly active antiretroviral therapy in patients with HIV infection.
Chi-Tai Fang,Pei-Jer Chen,Mao-Yuan Chen,Chien-Ching Hung,Shan-Chwen Chang,An-Lung Chang,Ding-Shinn Chen +6 more
TL;DR: Compared with previous studies, HAART containing lamivudine 300 mg/day effectively suppressed plasma HBV-DNA to 10(-3)-10(-5)-fold of the baseline levels, but a multi-phasic decay of HBV DNA was observed, and residual HBV replication persisted in most HBeAg-positive coinfected patients.
Journal ArticleDOI
Epidemiology of the viral hepatitis-HIV syndemic in San Francisco: a collaborative surveillance approach.
TL;DR: This analysis identified particular populations at risk for coinfection, which can be used by viral hepatitis and HIV screening, prevention, and treatment programs to integrate, enhance, target, and prioritize prevention services and clinical care within the community to maximize health outcomes.
Journal ArticleDOI
The Timing of Hepatitis B Virus (HBV) Immunization Relative to Human Immunodeficiency Virus (HIV) Diagnosis and the Risk of HBV Infection Following HIV Diagnosis
Michael L. Landrum,Michael L. Landrum,Katherine Huppler Hullsiek,Helen M. Chun,Nancy F. Crum-Cianflone,Nancy F. Crum-Cianflone,Anuradha Ganesan,Anuradha Ganesan,Amy C. Weintrob,Amy C. Weintrob,R. Vincent Barthel,Robert J. O'Connell,Robert J. O'Connell,Brian K. Agan +13 more
TL;DR: It is suggested that completion of the vaccine series prior to HIV infection may be the optimal strategy for preventing this significant comorbid infection in HIV-infected persons.
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Prevalence of immunity to hepatitis viruses A and B in a large cohort of HIV/HCV-coinfected patients, and factors associated with HAV and HBV vaccination
Maria Winnock,Firouzé Bani-Sadr,Elodie Pambrun,Marc-Arthur Loko,Caroline Lascoux-Combe,D. Garipuy,E. Rosenthal,Patrizia Carrieri,François Dabis,Dominique Salmon +9 more
TL;DR: HAV screening rates and HAV and HBV vaccination rates were low in this population of HIV/HCV-coinfected patients and the benefits of routine HAVand HBV screening, vaccination and post-vaccination testing should be emphasized.
Journal ArticleDOI
Persistence of vaccine immunity against hepatitis B virus and response to revaccination in vertically HIV-infected adolescents on HAART.
Silvana Duarte Pessoa,Maristela Miyamoto,Erika Ono,Aída F.T.B. Gouvêa,Maria Isabel de Moraes-Pinto,Regina Célia de Menezes Succi +5 more
TL;DR: It is concluded that lower immune activation, higher CD4+ T cell percentage and better control of HIV replication may be associated with hepatitis B vaccine response.
References
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Journal Article
Statistical methods in cancer research. Volume II--The design and analysis of cohort studies.
N. E. Breslow,N. E. Day +1 more
TL;DR: What do you do to start reading statistical methods in cancer research vol ii the design and analysis of cohort studies?
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The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994
Miriam J. Alter,Deanna Kruszon-Moran,Omana V. Nainan,Geraldine M. McQuillan,Fengxiang Gao,Linda A. Moyer,Richard A. Kaslow,Harold S. Margolis +7 more
TL;DR: The strongest factors independently associated with HCV infection were illegal drug use and high-risk sexual behavior, and poverty, having had 12 or fewer years of education, and having been divorced or separated were independently associated.
Journal ArticleDOI
Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients
Yves Benhamou,Marie Bochet,V. Di Martino,Frédéric Charlotte,F. Azria,Anne Coutellier,Michel Vidaud,François Bricaire,Pierre Opolon,Christine Katlama,Thierry Poynard +10 more
TL;DR: In coinfected patients, a low CD4 count, alcohol consumption rate, and age at HCV infection are associated with a higher liver fibrosis progression rate, while HIV seropositivity accelerates HCV‐related liver Fibrosis progression.
Journal ArticleDOI
The multicenter aids cohort study: rationale, organization, and selected characteristics of the participants
TL;DR: The Multicenter AIDS Cohort Study was designed to elucidate the natural history of the infection causing acquired immunodeficiency syndrome (AIDS), identify risk factors for occurrence and clinical expression of the virus, and establish a repository of biologic specimens for future study.
Journal ArticleDOI
Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
TL;DR: The data indicate that use of ritonavir may increase risk of severe hepatotoxicity, and does not support withholding protease inhibitor therapy from persons coinfected with hepatitis B or C virus.