Journal ArticleDOI
HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)
Chloe L. Thio,Eric C. Seaberg,Richard L. Skolasky,John P. Phair,Barbara R. Visscher,Alvaro Muñoz,David L. Thomas +6 more
TLDR
Individuals coinfected with HIV-1 and HBV, especially those with low CD4+ nadir counts, are at increased risk for liver-related mortality, underscoring the importance of prevention, identification, and comprehensive management of hepatitis B in people infected withAIDS.Citations
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HIV, hepatitis B virus, and hepatitis C virus co-infection in patients in the China National Free Antiretroviral Treatment Program, 2010–12: a retrospective observational cohort study
Fujie Zhang,Fujie Zhang,Hao Zhu,Yasong Wu,Zhihui Dou,Yao Zhang,Nora Kleinman,Marc Bulterys,Zunyou Wu,Ye Ma,Zhao D,Xia Liu,Hua Fang,Jing Liu,Weiping Cai,Hong Shang +15 more
TL;DR: Effective management for viral hepatitis should be integrated into HIV treatment programmes, and long-term data are needed about the effect of hepatitis co-infection on HIV disease progression.
Journal Article
Major role of hepatitis B genotypes in liver fibrosis during coinfection with HIV. Commentary
Karine Lacombe,Véronique Massari,Pierre-Marie Girard,Lawrence Serfaty,Joël Gozlan,Gilles Pialoux,Patrick Mialhes,Jean-Michel Molina,Caroline Lascoux-Combe,Dominique Wendum,Fabrice Carrat,Fabien Zoulim,Vincent Soriano,Julie Sheldon,Belén Ramos,Marina Núñez +15 more
TL;DR: In this article, a cross-sectional analysis examined common characteristics of hepatitis B virus infection in an ongoing cohort study of 308 patients with both HIV-1-positive Western blot and plasma HBV surface antigen (HBsAg) seropositivity.
Journal ArticleDOI
British HIV Association guidelines for HIV-associated malignancies 2014: BHIVA guidelines for HIV-associated malignancies 2014
Mark Bower,Adrian Palfreeman,Maryam Alfa-Wali,Christopher B Bunker,Fiona Burns,Duncan Churchill,Simon Collins,Kate Cwynarski,Simon Edwards,Paul Fields,Kate Fife,Eve Gallop-Evans,Shireen Kassam,Ranjababu Kulasegaram,Charles J.N. Lacey,Robert Marcus,Sylvia Montoto,Mark T. Nelson,Tom Newsom-Davis,Chloe Orkin,Kate Shaw,Melinda Tenant-Flowers,Andrew J. Webb,Sarah Westwell,Matthew Williams +24 more
Journal ArticleDOI
The challenge of AIDS-related malignancies in sub-Saharan Africa.
Annie J. Sasco,Antoine Jaquet,Emilie Boidin,Didier K. Ekouevi,Fabian Thouillot,Thomas LeMabec,Marie-Anna Forstin,Philippe Renaudier,Paul Ndom,Denis Malvy,François Dabis +10 more
TL;DR: It is shown that HIV infection is not only strongly associated with AIDS-classifying cancers but also provided some evidence of association for other neoplasia, and African countries need now to implement well designed population-based studies.
Journal ArticleDOI
Major role of hepatitis B genotypes in liver fibrosis during coinfection with HIV.
Karine Lacombe,Véronique Massari,Pierre-Marie Girard,Lawrence Serfaty,Joël Gozlan,Gilles Pialoux,Patrick Mialhes,Jean-Michel Molina,Caroline Lascoux-Combe,Dominique Wendum,Fabrice Carrat,Fabien Zoulim +11 more
TL;DR: HBV genotype G is a determinant of liver fibrosis in HIV/HBV-coinfected patients and HBV genotyping should be considered as part of the management of patients with multiple risk factors for rapid progression of Liver fibrosis.
References
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Journal Article
Statistical methods in cancer research. Volume II--The design and analysis of cohort studies.
N. E. Breslow,N. E. Day +1 more
TL;DR: What do you do to start reading statistical methods in cancer research vol ii the design and analysis of cohort studies?
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The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994
Miriam J. Alter,Deanna Kruszon-Moran,Omana V. Nainan,Geraldine M. McQuillan,Fengxiang Gao,Linda A. Moyer,Richard A. Kaslow,Harold S. Margolis +7 more
TL;DR: The strongest factors independently associated with HCV infection were illegal drug use and high-risk sexual behavior, and poverty, having had 12 or fewer years of education, and having been divorced or separated were independently associated.
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Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients
Yves Benhamou,Marie Bochet,V. Di Martino,Frédéric Charlotte,F. Azria,Anne Coutellier,Michel Vidaud,François Bricaire,Pierre Opolon,Christine Katlama,Thierry Poynard +10 more
TL;DR: In coinfected patients, a low CD4 count, alcohol consumption rate, and age at HCV infection are associated with a higher liver fibrosis progression rate, while HIV seropositivity accelerates HCV‐related liver Fibrosis progression.
Journal ArticleDOI
The multicenter aids cohort study: rationale, organization, and selected characteristics of the participants
TL;DR: The Multicenter AIDS Cohort Study was designed to elucidate the natural history of the infection causing acquired immunodeficiency syndrome (AIDS), identify risk factors for occurrence and clinical expression of the virus, and establish a repository of biologic specimens for future study.
Journal ArticleDOI
Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
TL;DR: The data indicate that use of ritonavir may increase risk of severe hepatotoxicity, and does not support withholding protease inhibitor therapy from persons coinfected with hepatitis B or C virus.