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Journal ArticleDOI

HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)

TLDR
Individuals coinfected with HIV-1 and HBV, especially those with low CD4+ nadir counts, are at increased risk for liver-related mortality, underscoring the importance of prevention, identification, and comprehensive management of hepatitis B in people infected withAIDS.
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Molecular Mechanisms Responsible for Occult Hepatitis B Virus Infection

TL;DR: All the conditions inducing host immunosuppression can cause the reactivation of OBI with the development of a typical overt hepatitis B infection, and other factors such as immune responses, viral mutations, epigenetic mechanisms, and co-infection are associated with occult infection.

Recommendations from a National Conference on Universal Vaccination Against Hepatitis B and Hepatitis A in Adults

TL;DR: Current recommendations of the CDC's Advisory Committee on Immunization Practices (ACIP) for hep- atitis B and hepatitis A vaccination in adults are based on a daunting list of risk groups, many of which overlap.
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Journal Article

Statistical methods in cancer research. Volume II--The design and analysis of cohort studies.

TL;DR: What do you do to start reading statistical methods in cancer research vol ii the design and analysis of cohort studies?
Journal ArticleDOI

The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994

TL;DR: The strongest factors independently associated with HCV infection were illegal drug use and high-risk sexual behavior, and poverty, having had 12 or fewer years of education, and having been divorced or separated were independently associated.
Journal ArticleDOI

Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients

TL;DR: In coinfected patients, a low CD4 count, alcohol consumption rate, and age at HCV infection are associated with a higher liver fibrosis progression rate, while HIV seropositivity accelerates HCV‐related liver Fibrosis progression.
Journal ArticleDOI

The multicenter aids cohort study: rationale, organization, and selected characteristics of the participants

TL;DR: The Multicenter AIDS Cohort Study was designed to elucidate the natural history of the infection causing acquired immunodeficiency syndrome (AIDS), identify risk factors for occurrence and clinical expression of the virus, and establish a repository of biologic specimens for future study.
Journal ArticleDOI

Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.

TL;DR: The data indicate that use of ritonavir may increase risk of severe hepatotoxicity, and does not support withholding protease inhibitor therapy from persons coinfected with hepatitis B or C virus.
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