Journal ArticleDOI
HIV-1, hepatitis B virus, and risk of liver-related mortality in the Multicenter Cohort Study (MACS)
Chloe L. Thio,Eric C. Seaberg,Richard L. Skolasky,John P. Phair,Barbara R. Visscher,Alvaro Muñoz,David L. Thomas +6 more
TLDR
Individuals coinfected with HIV-1 and HBV, especially those with low CD4+ nadir counts, are at increased risk for liver-related mortality, underscoring the importance of prevention, identification, and comprehensive management of hepatitis B in people infected withAIDS.Citations
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Seroprevalence of Hepatitis B Surface Antigen (HBsAg) Co-infections among HIV Positive Individuals. .
TL;DR: It is needful that all HIV positive patients be screened for HBsAg, while patients who lack the HBsAb and do not have theHBsAg positivity or occult HBV should be vaccinated against HBV so as to influence the clinical management of subjects on HARRT.
Journal Article
The prevalence of hepatitis B and C viruses among HIV sero discordant couples in Kisumu, Kenya
TL;DR: Since the prevalence of HBV was high, HBV prevention measures should be encouraged among HIV-1 sero-discordant couples to reduce HBV transmission rates among couples.
Dissertation
Hepatitis B coinfection in HIV-positive patients starting antiretroviral therapy
TL;DR: Coinfection was associated with an increased risk of exacerbations of liver inflammation, HIV progression and death, but deaths were not usually liver-related, and have implications for the management of HBV coinfection in resourcepoor settings.
Journal ArticleDOI
Antiretroviral Effects on HBV/HIV Co-infection and the Natural History of Liver Disease.
TL;DR: It is recommended thatHBV-HIV coinfected persons be treated with ART regimens containing tenofovir, as long-term studies have yet to demonstrate a profound positive impact of ART on HBV-related fibrosis progression and development of endstage liver disease.
References
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Journal Article
Statistical methods in cancer research. Volume II--The design and analysis of cohort studies.
N. E. Breslow,N. E. Day +1 more
TL;DR: What do you do to start reading statistical methods in cancer research vol ii the design and analysis of cohort studies?
Journal ArticleDOI
The Prevalence of Hepatitis C Virus Infection in the United States, 1988 through 1994
Miriam J. Alter,Deanna Kruszon-Moran,Omana V. Nainan,Geraldine M. McQuillan,Fengxiang Gao,Linda A. Moyer,Richard A. Kaslow,Harold S. Margolis +7 more
TL;DR: The strongest factors independently associated with HCV infection were illegal drug use and high-risk sexual behavior, and poverty, having had 12 or fewer years of education, and having been divorced or separated were independently associated.
Journal ArticleDOI
Liver fibrosis progression in human immunodeficiency virus and hepatitis C virus coinfected patients
Yves Benhamou,Marie Bochet,V. Di Martino,Frédéric Charlotte,F. Azria,Anne Coutellier,Michel Vidaud,François Bricaire,Pierre Opolon,Christine Katlama,Thierry Poynard +10 more
TL;DR: In coinfected patients, a low CD4 count, alcohol consumption rate, and age at HCV infection are associated with a higher liver fibrosis progression rate, while HIV seropositivity accelerates HCV‐related liver Fibrosis progression.
Journal ArticleDOI
The multicenter aids cohort study: rationale, organization, and selected characteristics of the participants
TL;DR: The Multicenter AIDS Cohort Study was designed to elucidate the natural history of the infection causing acquired immunodeficiency syndrome (AIDS), identify risk factors for occurrence and clinical expression of the virus, and establish a repository of biologic specimens for future study.
Journal ArticleDOI
Hepatotoxicity associated with antiretroviral therapy in adults infected with human immunodeficiency virus and the role of hepatitis C or B virus infection.
TL;DR: The data indicate that use of ritonavir may increase risk of severe hepatotoxicity, and does not support withholding protease inhibitor therapy from persons coinfected with hepatitis B or C virus.