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Bruce S. McEwen
Researcher at Rockefeller University
Publications - 1168
Citations - 214913
Bruce S. McEwen is an academic researcher from Rockefeller University. The author has contributed to research in topics: Hippocampus & Hippocampal formation. The author has an hindex of 215, co-authored 1163 publications receiving 200638 citations. Previous affiliations of Bruce S. McEwen include Yale University & National Institutes of Health.
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Book
Sexual Differentiation of the Brain: Based on a Work Session of the Neurosciences Research Program
Robert W. Goy,Bruce S. McEwen +1 more
TL;DR: This book, based on a Work Session of MIT's Neurosciences Research Program, presents a balanced account of a controversial topic--the relative importance of genes, hormones, and environment in the formation of sexual behavior.
Journal ArticleDOI
Depletion of polysialic acid from neural cell adhesion molecule (PSA-NCAM) increases CA3 dendritic arborization and increases vulnerability to excitotoxicity.
Trudy J. McCall,Zachary M. Weil,Juan Nacher,Erik B. Bloss,Abderrahman El Maarouf,Urs Rutishauser,Bruce S. McEwen +6 more
TL;DR: It is shown that enzymatic removal of PSA produced a remarkable expansion of dendritic arbors of CA3 pyramidal neurons, with a lesser effect in CA1, which supports the hypothesis that CA3 arbor plasticity plays a protective role during prolonged stress and clarifies the role of PPA-NCAM in stress-induced dendrite plasticity.
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Biochemical and radioautographic analysis of estrogen-inducible progestin receptors in female ferret brain and pituitary: correlations with effects of progesterone on sexual behavior and gonadotropin-releasing hormone-stimulated secretion of luteinizing hormone.
TL;DR: Differences in the ability of progesterone to facilitate or inhibit sexual receptivity are not readily explained by species differences in the neural distribution of estrogen-induced progestin receptors.
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Moderate exercise ameliorates dysregulated hippocampal glycometabolism and memory function in a rat model of type 2 diabetes.
Takeru Shima,Takashi Matsui,Takashi Matsui,Subrina Jesmin,Masahiro Okamoto,Masahiro Okamoto,Mariko Soya,Koshiro Inoue,Yu Fan Liu,Ignacio Torres-Aleman,Bruce S. McEwen,Hideaki Soya +11 more
TL;DR: These findings are the first to describe detailed profiles of glycometabolism in the type 2 diabetic hippocampus and to show that 4 weeks of moderate exercise improves memory dysfunction in type 2 diabetes via amelioration of dysregulated hippocampal glycomETabolism.
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Testosterone decrease does not play a major role in the suppression of hippocampal cell proliferation following social defeat stress in rats.
TL;DR: The results indicate that repeated social defeat stress on 5 successive days induces a significant drop in plasma testosterone levels in male rats and suppresses hippocampal cell proliferation 24h and 3weeks after the end of the stress period.