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Bruce S. McEwen

Researcher at Rockefeller University

Publications -  1168
Citations -  214913

Bruce S. McEwen is an academic researcher from Rockefeller University. The author has contributed to research in topics: Hippocampus & Hippocampal formation. The author has an hindex of 215, co-authored 1163 publications receiving 200638 citations. Previous affiliations of Bruce S. McEwen include Yale University & National Institutes of Health.

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Peripheral glucose administration stimulates the translocation of GLUT8 glucose transporter to the endoplasmic reticulum in the rat hippocampus.

TL;DR: It is demonstrated that GLUT8 undergoes rapid translocation to the rough ER in the rat hippocampus following peripheral glucose administration, trafficking that is impaired in STZ diabetes, suggesting that insulin serves as a stimulus forGLUT8 translocation in hippocampal neurons.
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Rapid transport of radioactivity in goldfish optic nerve following injections of labelled glucosamine

TL;DR: Tritiated glucosamine injected into the goldfish eye is incorporated into acid-insoluble and chloroform-methanol-extractable materials which are rapidly transported through the optic nerve to the contralateral optic tectum, suggesting that labeling with amino sugars may be a specific way of demonstrating fast axoplasmic transport.
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Endocannabinoids: The silent partner of glucocorticoids in the synapse.

TL;DR: New light is shed on the rapid effects of glucocorticoids in mammals by revealing a putative nongenomic role of glucose-like receptors in regulating emotional learning in rodents through a coordinated induction of endocannabinoid signaling.
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Glucocorticoids regulate the concentration of glial fibrillary acidic protein throughout the brain.

TL;DR: The expression of GFAP throughout the brain appears to be physiologically regulated by adrenal glucocorticoids.