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Bruce S. McEwen
Researcher at Rockefeller University
Publications - 1168
Citations - 214913
Bruce S. McEwen is an academic researcher from Rockefeller University. The author has contributed to research in topics: Hippocampus & Hippocampal formation. The author has an hindex of 215, co-authored 1163 publications receiving 200638 citations. Previous affiliations of Bruce S. McEwen include Yale University & National Institutes of Health.
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Developing forebrain astrocytes are sensitive to thyroid hormone
TL;DR: Quantitative analyses revealed significant increases in the density of GFAP‐immunostained astrocytes and in the cross‐sectional cell body area and the number of primary processes in Golgi‐impregnated astroCytes of the basal forebrain and hippocampus of animals treated neonatally with thyroid hormone.
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Steroid and barbiturate modulation of the GABAa receptor. Possible mechanisms.
TL;DR: This review describes the modulation of the GABAa receptor by steroid hormones and barbiturates and proposes guidelines for further research on the basis of considerable evidence to understand the molecular mechanisms by which steroid hormones modulate the receptor.
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Volumetric structural magnetic resonance imaging (MRI) of the rat hippocampus following kainic acid (KA) treatment.
Oliver T. Wolf,Victor V. Dyakin,A. Patel,Csaba Vadasz,Csaba Vadasz,M. J. de Leon,M. J. de Leon,Bruce S. McEwen,Karen Bulloch +8 more
TL;DR: The histological observations supported the MRI data showing neuronal loss and neuronal degeneration in CA1 and CA3 of the hippocampus, which was accompanied by strong microglia activation, and demonstrated a reliable and valid method for the measurement of the rat hippocampus in vivo using MRI with a high field magnet.
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Distribution of alpha 2-adrenergic receptors in the brain of the Japanese quail as determined by quantitative autoradiography: implications for the control of sexually dimorphic reproductive processes.
TL;DR: With the use of [3H]p-aminoclonidine (PAC), alpha 2-adrenergic binding sites were mapped in the brain of the Japanese quail and no sexual dimorphism in density of receptor binding was identified.
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Chronic social stress: Changes in behavioral and physiological indices of emotion
Robert J. Blanchard,Mark A. Hebert,Randall R. Sakai,Christina R. McKittrick,Andy Henrie,Errol Yudko,Bruce S. McEwen,D. Caroline Blanchard +7 more
TL;DR: Comparisons of patterns of stress response with those of other chronic stress models such as learned helplessness and chronic mild stress suggest that, in terms of adrenal and gonadal steroid hormone response, subordination constitutes a more severe stressor.