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Bruce S. McEwen
Researcher at Rockefeller University
Publications - 1168
Citations - 214913
Bruce S. McEwen is an academic researcher from Rockefeller University. The author has contributed to research in topics: Hippocampus & Hippocampal formation. The author has an hindex of 215, co-authored 1163 publications receiving 200638 citations. Previous affiliations of Bruce S. McEwen include Yale University & National Institutes of Health.
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Estrogen and progestin receptors appear in transplanted fetal hypothalamus-preoptic area independently of the steroid environment.
TL;DR: Estrogen receptors were assayed in HPOA 8 weeks after transplantation of the tissue from embryonic day 15 to 18 fetuses and found to be biochemically functional as indicated by the ability of acute estrogen treatment to induce progestin receptors in the transplants.
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Regional specificity in estradiol effects on [3H]uridine incorporation in rat brain
TL;DR: The results indicate that the effects of estradiol on levels of newly synthesized RNA vary in a functionally and regionally specific manner within the brain.
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The untapped power of allostasis promoted by healthy lifestyles.
TL;DR: An evolutionary view helps to see mood as the product of interactions between neurobiological mechanisms and the structures the authors give to their societies and environments.
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Childhood trauma and insulin resistance in patients suffering from depressive disorders.
Carla Nasca,Kathleen Watson-Lin,Benedetta Bigio,Thalia K. Robakis,Alison Myoraku,Tonita E. Wroolie,Bruce S. McEwen,Natalie L. Rasgon,Natalie L. Rasgon +8 more
TL;DR: It is suggested that Fam‐Hx‐Dm2 and emotional abuse represent separate risk factors for developing metabolic dysfunction in patients suffering from MDD, and that the effects of emotional abuse on psychiatric illness may depend upon the personal characteristics, including Fam‐ Hx‐DM2.
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Quantitative autoradiography of [3H]piquindone binding sites (dopamine D2 receptors) in rat brain.
TL;DR: In vitro quantitative autoradiography indicated that binding sites of [3H](-)piquindone are localized to olfactory tubercle, accumbens nucleus, caudate putamen, cell bridges between caudates putamen and olfaction, and substantia nigra, which means that binding in these areas is stereoselective since it is found no specific binding with [ 3H](+)piquinone, the biologically inactive enantiomer.