Bruce S. McEwen

TL;DR: It is shown that Apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-1 (APOBEC1), together with its cofactor RBM47, mediates robust editing in different tissues and that APOBec1-mediated transcriptome diversification is required for the fine-tuning of protein expression in monocytes, suggesting an epitranscriptomic mechanism for the proper maintenance of homeostasis in innate immune cells.

TL;DR: The results suggest that hormonal factors regulate calmodulin gene expression in adult brain, and further evidence is required to establish the temporal interrelationships between steroid regulation of cal modulin and its target proteins.

TL;DR: The results indicate that there are some marked effects of a constant replacement source of corticosterone on the cyclical occurrence of both activity and sleep.

TL;DR: In vivo corticosterone modulates its own number of binding sites demonstrated by in vitro binding on brain sections, in a manner which is reminiscent of changes in cytosol receptors demonstrated by conventional biochemical methods, Thus, this in vitro method provides an alternative way to study the plasticity of hippocampal glucocorticoid receptors.

TL;DR: It is proposed that increased estrogen receptor binding in the amygdala may provide a biochemical basis for the increased estrogen sensitivity found in olfactory bulbectomized female rats.