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Bruce S. McEwen
Researcher at Rockefeller University
Publications - 1168
Citations - 214913
Bruce S. McEwen is an academic researcher from Rockefeller University. The author has contributed to research in topics: Hippocampus & Hippocampal formation. The author has an hindex of 215, co-authored 1163 publications receiving 200638 citations. Previous affiliations of Bruce S. McEwen include Yale University & National Institutes of Health.
Papers
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Journal ArticleDOI
Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology
Daniel C. Cole,Youngcheul Chung,Khatuna Gagnidze,Kaitlyn H. Hajdarovic,Violeta Rayon-Estrada,Dewi Harjanto,Benedetta Bigio,Judit Gal-Toth,Teresa A. Milner,Teresa A. Milner,Bruce S. McEwen,F. Nina Papavasiliou,F. Nina Papavasiliou,Karen Bulloch +13 more
TL;DR: It is found that, within MG, an RNA-editing function performed by the deaminase APOBEC1 and its obligate cofactor affects protein expression levels necessary for harmonious function within these cells and the cells they support.
Journal ArticleDOI
Adrenocortical steroids modify neurotransmitter-stimulated cyclic AMP accumulation in the hippocampus and limbic brain of the rat.
TL;DR: It is demonstrated that glucocorticoids regulate neurotransmit‐mitter‐stimulated cyclic AMP generation in a fashion that is specific, both for the neurotransmitter involved and for the brain regions affected.
Book ChapterDOI
Actions of sex hormones on the brain: 'organization' and 'activation' in relation to functional teratology.
TL;DR: This chapter investigates the basic neuroendocrinology underlying gonadal steroid actions on the developing and adult brain and examines the impact of gonadal hormones on the nervous system related to the functional teratologies.
Journal ArticleDOI
Adrenal Steroid Receptors in the PVN: Studies with Steroid Antagonists in Relation to Macronutrient Intake
TL;DR: Results indicate that the feeding elicited by CORT at dark onset is dependent upon the functional integrity of type II glucocorticoid receptors within the PVN, in contrast to the feeding elicit by ALDO which is dependent on endogenous type I steroid receptor activation within this nucleus.
Journal ArticleDOI
Gonadal steroid modulation of neurotransmitter-stimulated cAMP accumulation in the hippocampus of the rat.
TL;DR: The results suggest that gonadal and other steroids may specifically modulate the responsiveness of components of the adenylate cyclase system to certain neurotransmitters, and that such regulation may differ between the sexes and may occur in telencephalic brain regions such as the hippocampus.