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Bruce S. McEwen
Researcher at Rockefeller University
Publications - 1168
Citations - 214913
Bruce S. McEwen is an academic researcher from Rockefeller University. The author has contributed to research in topics: Hippocampus & Hippocampal formation. The author has an hindex of 215, co-authored 1163 publications receiving 200638 citations. Previous affiliations of Bruce S. McEwen include Yale University & National Institutes of Health.
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Book ChapterDOI
Chapter 19 Resolving a mystery: progress in understanding the function of adrenal steroid receptors in hippocampus
Bruce S. McEwen,Heather A. Cameron,Helen M. Chao,Elizabeth Gould,Victoria N. Luine,Ana Maria Magarinos,Constantine Pavlides,Robert L. Spencer,Yoshifumi Watanabe,Catherine S. Woolley +9 more
TL;DR: The chapter discusses the interactive roles that are played by thyroid hormone balance, sex hormones, and gender, together with the actions of adrenal steroids, in determining the ability of the hippocampus to change its structure and function in response to the external environment.
Journal ArticleDOI
Oestrogen receptors in cell nuclei of the hypothalamus-preoptic area-amygdala following an injection of oestradiol or the antioestrogen CI-628.
Edward J. Roy,Bruce S. McEwen +1 more
TL;DR: The maximum level of receptors produced in the HPA cell nuclei following CI-628 treatment was lower than the peak level of nuclear receptors following oestradiol, and the dissociation rate in vitro of nuclear antioestrogen-receptor complexes formed in vivo was more rapid at 0 degrees C than that of nuclear oestrateceptor complexes.
Journal ArticleDOI
Dexamethasone up-regulates mRNA for Na+,K(+)-ATPase in some spinal cord neurones after cord transection.
Susana L. González,Claudia Grille,Maria Claudia Gonzalez Deniselle,Analia Lima,Bruce S. McEwen,Alejandro F. De Nicola +5 more
TL;DR: It is suggested that up-regulation of mRNA expression for Na+,K+-ATPase may constitute an important mechanism by which glucocorticoids help to re-establish neuronal function after spinal cord injury.
Journal ArticleDOI
Pharmacological characterization of central and peripheral type I and type II adrenal steroid receptors in the prairie vole, a glucocorticoid-resistant rodent.
TL;DR: A detailed pharmacological characterization of intracellular type I and type II adrenal steroid receptors in peripheral tissues and the hippocampus of the prairie vole and the Sprague Dawley rat was provided in this paper.
Journal ArticleDOI
Effects of in vivo estradiol and progesterone on tritiated flunitrazepam binding in rat spinal cord.
TL;DR: Spinal transection flunitrazepam binding in endocrine controls and estradiol-treated animals was unchanged but a progesterone injection 4-5 h before being killed had no effect on binding in the substantia gelatinosa.