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Bruce S. McEwen

Researcher at Rockefeller University

Publications -  1168
Citations -  214913

Bruce S. McEwen is an academic researcher from Rockefeller University. The author has contributed to research in topics: Hippocampus & Hippocampal formation. The author has an hindex of 215, co-authored 1163 publications receiving 200638 citations. Previous affiliations of Bruce S. McEwen include Yale University & National Institutes of Health.

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Book ChapterDOI

Glucocorticoid binding sites in rat brain: subcellular and anatomical localizations.

TL;DR: The chemistry of glucocorticoid action in brain by following the interaction of the hormone itself with this organ is reviewed, with results serving to direct attention to a particular cellular mechanism of hormone action and to certain brain regions for further neurochemical and physiological studies.
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Sex steroid receptors in the perinatal rat brain

TL;DR: The possible involvement of these receptors in sexual differentiation of the brain is suggested by the finding that an antiandrogen inhibits both the binding of androgens (but not estrogens) and the differentiation of males.
Journal ArticleDOI

Sex differences in subcellular distribution of delta opioid receptors in the rat hippocampus in response to acute and chronic stress.

TL;DR: Data indicate that DORs redistribute within CA3 pyramidal cells and dentate hilar GABAergic interneurons in a sexually dimorphic manner that would promote activation and drug related learning in males after AIS and in females after CIS.
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Dehydroepiandrosterone (DHEA) metabolism in the brain: identification by liquid chromatography/mass spectrometry of the delta-4-isomer of DHEA and related steroids formed from androstenedione by mouse BV2 microglia.

TL;DR: Its identity as 3beta-hydroxy-4-androstene-17-one, the Delta(4)-isomer of DHEA, was confirmed by mass spectrometry (LC/MS), as well as by reverse isotope dilution analysis involving co-crystallization with the synthetic steroid.
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Stress-induced out-of-context activation of memory.

TL;DR: An intensely stressful experience can itself activate memories that are unrelated to the stressful experience, and this previously unknown property of stress could help explain how traumatic memories become pathological.