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Bruce S. McEwen
Researcher at Rockefeller University
Publications - 1168
Citations - 214913
Bruce S. McEwen is an academic researcher from Rockefeller University. The author has contributed to research in topics: Hippocampus & Hippocampal formation. The author has an hindex of 215, co-authored 1163 publications receiving 200638 citations. Previous affiliations of Bruce S. McEwen include Yale University & National Institutes of Health.
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Journal ArticleDOI
Sex differences in the regulation of oxytocin receptors by ovarian steroids in the ventromedial hypothalamus of the rat.
TL;DR: The behavioral insensitivity of male rats to ovarian hormones, in particular to P, may be related to sex differences affecting the modulation of OTR binding.
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Introduction for the allostatic load special issue.
Achim Peters,Bruce S. McEwen +1 more
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Cognitive Effects of Intravenous Hydrocortisone in Subjects with PTSD and Healthy Control Subjects
Robert A. Grossman,Robert A. Grossman,Rachel Yehuda,Rachel Yehuda,Julia A. Golier,Julia A. Golier,Bruce S. McEwen,Philip D. Harvey,Philip D. Harvey,Nelly Sta. Maria +9 more
TL;DR: Brain sensitivity to glucocorticoids appears to be greater in subjects with PTSD, and heightened vulnerability of declarative memory in Subjects with PTSD may indicate hippocampal involvement, whereas working memory vulnerability suggests additional brain regions (prefrontal, cingulate, temporal, and parietal cortices) and neurotransmitter systems (dopamine and serotonin) particularly sensitive to glucomethasone in persons with PTSD.
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Steroids and brain function
TL;DR: The new evidence pointing to diverse regulatory effects which steroids produce on developmental and neurochemical processes in receptor-containing cell groupings within the nervous system is described.
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Investigating the Burden of Chronic Pain: An Inflammatory and Metabolic Composite
Kimberly T. Sibille,Ólöf Anna Steingrímsdóttir,Roger B. Fillingim,Audun Stubhaug,Henrik Schirmer,Huaihou Chen,Bruce S. McEwen,Christopher Sivert Nielsen +7 more
TL;DR: The risk factor composite was higher in individuals with chronic pain, greater with increasing pain severity, and influenced by health behaviors, which would have significant clinical and research utility.