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Bruce S. McEwen
Researcher at Rockefeller University
Publications - 1168
Citations - 214913
Bruce S. McEwen is an academic researcher from Rockefeller University. The author has contributed to research in topics: Hippocampus & Hippocampal formation. The author has an hindex of 215, co-authored 1163 publications receiving 200638 citations. Previous affiliations of Bruce S. McEwen include Yale University & National Institutes of Health.
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Journal ArticleDOI
Estrogen induces phosphorylation of cyclic AMP response element binding (pCREB) in primary hippocampal cells in a time-dependent manner.
TL;DR: The central role played by CaMKII pathway in the actions of E on both transcriptional regulation and structural reorganization in neurons is demonstrated, demonstrating the importance of hippocampal primary cell cultures for these studies.
Journal ArticleDOI
Brain dendritic cells in ischemic stroke: Time course, activation state, and origin
Jennifer C. Felger,Takato Abe,Ulrike W. Kaunzner,Andres Gottfried-Blackmore,Judit Gal-Toth,Bruce S. McEwen,Costantino Iadecola,Karen Bulloch +7 more
TL;DR: High levels of MHC II and the co-stimulatory molecule CD80 on bDC at 72 h corresponded to peak lymphocyte infiltration, and suggested a functional interaction between these two immune cell populations.
Book ChapterDOI
Glucocorticoids and Hippocampus: Receptors in Search of a Function
TL;DR: The identification of putative receptor sites was the impetus for the search for the function of glucocorticoids in hippocampus and in the rest of the brain and that search now seems to be coming to fruition.
Journal ArticleDOI
Studies of hormone action in the hippocampal formation: Possible relevance to depression and diabetes
TL;DR: The hippocampus is a brain structure involved in episodic, declarative, contextual and spatial learning and memory as well as its being a component in the control of autonomic and vegetative functions such as ACTH secretion, and its possible role in the regulation of glucose homeostasis.
Journal ArticleDOI
Further studies of brain aldosterone binding sites employing new mineralocorticoid and glucocorticoid receptor markers in vitro.
Héctor Coirini,Ana Mari´a Magarin˜os,Alejandro F. De Nicola,Thomas C. Rainbow,Bruce S. McEwen +4 more
TL;DR: The usefulness of these synthetic markers in identifying MC binding sites in several brain regions and also in the hippocampus during ontogenetic development is demonstrated.