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Bruce S. McEwen
Researcher at Rockefeller University
Publications - 1168
Citations - 214913
Bruce S. McEwen is an academic researcher from Rockefeller University. The author has contributed to research in topics: Hippocampus & Hippocampal formation. The author has an hindex of 215, co-authored 1163 publications receiving 200638 citations. Previous affiliations of Bruce S. McEwen include Yale University & National Institutes of Health.
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Journal ArticleDOI
Chronic immobilization stress alters aspects of emotionality and associative learning in the rat.
TL;DR: The authors present two experiments examining emotional and learned responses to CIS, and report significant effects of CIS on aggression, inhibitory avoidance, escape, as well as learned aspects of fear in rats.
Journal ArticleDOI
Chronic exposure to stress levels of corticosterone alters GABAA receptor subunit mRNA levels in rat hippocampus
TL;DR: It is demonstrated that chronic exposure to stress levels of CORT produces complex changes in the mRNA levels of multiple GABAA receptor subunits, independently of the CORT-induced suppression of circulating testosterone.
Journal ArticleDOI
Regulation of high-affinity GABAA receptors in the dorsal hippocampus by estradiol and progesterone
TL;DR: Results suggest that estrogens may regulate the activity of specific hippocampal neurons by modulating their sensitivity to GABA.
Journal ArticleDOI
Pubertal maturation and time of day differentially affect behavioral and neuroendocrine responses following an acute stressor.
TL;DR: Puberty markedly influences stress responsiveness such that prepubertal animals show a more protracted corticosterone and progesterone response following acute stress compared to adults, and time of day interact to modulate post-stress behavior and demonstrate a dissociation between post- stress hormonal and behavioral responses.
Book ChapterDOI
Posttraumatic stress disorder, allostatic load, and medical illness.
TL;DR: In this paper, the authors present a psychobiological conceptual framework that accounts for mounting evidence that posttraumatic stress disorder (PTSD) is a risk factor for medical illness.