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Bruce S. McEwen
Researcher at Rockefeller University
Publications - 1168
Citations - 214913
Bruce S. McEwen is an academic researcher from Rockefeller University. The author has contributed to research in topics: Hippocampus & Hippocampal formation. The author has an hindex of 215, co-authored 1163 publications receiving 200638 citations. Previous affiliations of Bruce S. McEwen include Yale University & National Institutes of Health.
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Corticosteroid binding in rat brain and pituitary cytosols: resolution of multiple binding components by polyacrylamide gel based isoelectric focusing
TL;DR: It seems essential, in order to firmly establish the existence of different populations of central nervous and pituitary corticosteroid receptor sites, that these sites should be separated and demonstrated to be distinct.
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Steroid and thyroid hormones modulate a changing brain
Bruce S. McEwen,Héctor Coirini,Anita Danielsson,Maya Frankfurt,Elizabeth Gould,Scott D. Mendelson,Michael Schumacher,Annabell C. Segarra,Catherine S. Woolley +8 more
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Behavioral and biological effects of chronic S18986, a positive AMPA receptor modulator, during aging.
Erik B. Bloss,Richard G. Hunter,Elizabeth M. Waters,Carmen Munoz,Katie Bernard,Bruce S. McEwen +5 more
TL;DR: Chronic, oral administration of S18986 increases locomotor activity and performance in a spatial memory task in aged rodents and attenuates the age-related increase in the expression of a microglial marker in the hippocampus, providing a framework for further studies of the potentially beneficial effects of AMPAR modulators on brain aging.
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Changes at multiple levels of the hypothalamo-pituitary adrenal axis following repeated electrically induced seizures
TL;DR: It is suggested that chronic ECS has a trophic effect on Type I receptors and that the higher levels of corticosterone resulting from chronic E CS do not induce adrenal steroid receptor down-regulation.
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Effects of the phytoestrogen coumestrol on locomotor and fear-related behaviors in female mice.
TL;DR: COUM might disrupt estrogen-enhanced locomotor activity by altering the dynamic by which EB acts on the brain through these two ER isoforms, and the conditioned fear result suggests that COUM may produce additional effects through alternative pathways.