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Carlos N. Pato

Researcher at Rutgers University

Publications -  17
Citations -  2121

Carlos N. Pato is an academic researcher from Rutgers University. The author has contributed to research in topics: Schizophrenia & Schizophrenia (object-oriented programming). The author has an hindex of 12, co-authored 17 publications receiving 1581 citations. Previous affiliations of Carlos N. Pato include Zilkha Neurogenetic Institute & Brown University.

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Journal ArticleDOI

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Bjarni J. Vilhjálmsson, +394 more
- 01 Oct 2015 - 
TL;DR: LDpred is introduced, a method that infers the posterior mean effect size of each marker by using a prior on effect sizes and LD information from an external reference panel, and outperforms the approach of pruning followed by thresholding, particularly at large sample sizes.
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Interrogating the Genetic Determinants of Tourette’s Syndrome and Other Tic Disorders Through Genome-Wide Association Studies

Dongmei Yu, +81 more
- 01 Mar 2019 - 
TL;DR: Modulation of gene expression through noncoding variants, particularly within cortico-striatal circuits, is implicated as a fundamental mechanism in Tourette's syndrome pathogenesis, supporting the unification of Tourette’s syndrome and other tic disorders in future diagnostic schemata.
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GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores

Niamh Mullins, +117 more
- 05 Jun 2019 - 
TL;DR: This study provides new information on genetic associations and demonstrates that genetic liability for major depression increases risk for suicide attempt across psychiatric disorders.
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Review of the putative association of dopamine D2 receptor and alcoholism: a meta-analysis.

Carlos N. Pato, +4 more
- 15 Jul 1993 - 
TL;DR: Overall, the meta-analysis of the results from all 8 studies supported a statistically significant association between the A1 allele of DRD2 and alcoholism, with an apparent increase in relative risk associated with increased severity of alcoholism.
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Effects of the acute administration of caffeine in patients with schizophrenia.

Peter Lucas, +5 more
- 01 Jul 1990 - 
TL;DR: It is shown that caffeine increases arousal and has a psychotogenic effect when administered to schizophrenic patients, and some measures of psychopathology were significantly increased.