scispace - formally typeset
S

Steve McCarroll

Researcher at Broad Institute

Publications -  28
Citations -  21430

Steve McCarroll is an academic researcher from Broad Institute. The author has contributed to research in topics: Population & Genome-wide association study. The author has an hindex of 17, co-authored 28 publications receiving 19776 citations. Previous affiliations of Steve McCarroll include Massachusetts Institute of Technology & Harvard University.

Papers
More filters
Journal ArticleDOI

A haplotype map of the human genome

John W. Belmont, +232 more
TL;DR: A public database of common variation in the human genome: more than one million single nucleotide polymorphisms for which accurate and complete genotypes have been obtained in 269 DNA samples from four populations, including ten 500-kilobase regions in which essentially all information about common DNA variation has been extracted.
Journal ArticleDOI

A second generation human haplotype map of over 3.1 million SNPs

Kelly A. Frazer, +237 more
- 18 Oct 2007 - 
TL;DR: The Phase II HapMap is described, which characterizes over 3.1 million human single nucleotide polymorphisms genotyped in 270 individuals from four geographically diverse populations and includes 25–35% of common SNP variation in the populations surveyed, and increased differentiation at non-synonymous, compared to synonymous, SNPs is demonstrated.
Journal ArticleDOI

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

Benjamin F. Voight, +183 more
- 01 Jul 2010 - 
TL;DR: By combining genome-wide association data from 8,130 individuals with type 2 diabetes and 38,987 controls of European descent and following up previously unidentified meta-analysis signals, 12 new T2D association signals are identified with combined P < 5 × 10−8.
Journal ArticleDOI

Genome-wide detection and characterization of positive selection in human populations

Pardis C. Sabeti, +258 more
- 18 Oct 2007 - 
TL;DR: ‘Long-range haplotype’ methods, which were developed to identify alleles segregating in a population that have undergone recent selection, and new methods that are based on cross-population comparisons to discover alleles that have swept to near-fixation within a population are developed.
Journal Article

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk (vol 42, pg 105, 2010)

Josée Dupuis, +303 more
- 01 May 2010 -