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Kung Yee Liang

Researcher at Johns Hopkins University

Publications -  64
Citations -  9725

Kung Yee Liang is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Linkage disequilibrium & Anxiety disorder. The author has an hindex of 36, co-authored 64 publications receiving 8714 citations. Previous affiliations of Kung Yee Liang include University of Baltimore & National Yang-Ming University.

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Genome-wide association study identifies five new schizophrenia loci

Stephan Ripke, +210 more
- 01 Oct 2011 - 
TL;DR: The authors examined the role of common genetic variation in schizophrenia in a genome-wide association study of substantial size: a stage 1 discovery sample of 21,856 individuals of European ancestry and a stage 2 replication sample of 29,839 independent subjects.
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Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Bjarni J. Vilhjálmsson, +394 more
- 01 Oct 2015 - 
TL;DR: LDpred is introduced, a method that infers the posterior mean effect size of each marker by using a prior on effect sizes and LD information from an external reference panel, and outperforms the approach of pruning followed by thresholding, particularly at large sample sizes.
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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Christian R. Marshall, +329 more
- 01 Jan 2017 - 
TL;DR: In this article, a centralized analysis pipeline was applied to a SCZ cohort of 21,094 cases and 20,227 controls, and a global enrichment of copy number variants (CNVs) was observed in cases (odds ratio (OR) = 1.11, P = 5.7 × 10-15), which persisted after excluding loci implicated in previous studies.
Posted ContentDOI

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

Christian R. Marshall, +255 more
- 23 Feb 2016 - 
TL;DR: A collaborative effort in which a centralized analysis pipeline is applied to a SCZ cohort, finding support at a suggestive level for nine additional candidate susceptibility and protective loci, which consist predominantly of CNVs mediated by non-allelic homologous recombination (NAHR).
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A family study of obsessive-compulsive disorder.

Gerald Nestadt, +8 more
- 01 Apr 2000 - 
TL;DR: Obsessive-compulsive disorder is a familial disorder and age at onset of OCD is valuable in characterizing a familial subtype, more specific to the phenotype than are compulsions.