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Michele T. Pato

Researcher at Rutgers University

Publications -  6
Citations -  1572

Michele T. Pato is an academic researcher from Rutgers University. The author has contributed to research in topics: Genome-wide association study & Tourette syndrome. The author has an hindex of 5, co-authored 6 publications receiving 1106 citations. Previous affiliations of Michele T. Pato include Zilkha Neurogenetic Institute & Semel Institute for Neuroscience and Human Behavior.

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Journal ArticleDOI

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Bjarni J. Vilhjálmsson, +394 more
- 01 Oct 2015 - 
TL;DR: LDpred is introduced, a method that infers the posterior mean effect size of each marker by using a prior on effect sizes and LD information from an external reference panel, and outperforms the approach of pruning followed by thresholding, particularly at large sample sizes.
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Interrogating the Genetic Determinants of Tourette’s Syndrome and Other Tic Disorders Through Genome-Wide Association Studies

Dongmei Yu, +81 more
- 01 Mar 2019 - 
TL;DR: Modulation of gene expression through noncoding variants, particularly within cortico-striatal circuits, is implicated as a fundamental mechanism in Tourette's syndrome pathogenesis, supporting the unification of Tourette’s syndrome and other tic disorders in future diagnostic schemata.
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Review of the putative association of dopamine D2 receptor and alcoholism: a meta-analysis.

Carlos N. Pato, +4 more
- 15 Jul 1993 - 
TL;DR: Overall, the meta-analysis of the results from all 8 studies supported a statistically significant association between the A1 allele of DRD2 and alcoholism, with an apparent increase in relative risk associated with increased severity of alcoholism.
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Copy number variation in obsessive-compulsive disorder and tourette syndrome : a cross-disorder study

Lauren M. McGrath, +121 more
- 01 Aug 2014 - 
TL;DR: Several converging lines of evidence implicate 16p13.11 deletions in OCD, with weaker evidence for a role in TS, and the trend toward increased overall CNV burden in TS and OCD suggests that deletions previously associated with other neurodevelopmental disorders may also contribute to these phenotypes.
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Erratum: Genome-wide association study of obsessive-compulsive disorder

S. E. Stewart, +108 more
- 01 Jul 2013 - 
TL;DR: The name of co-author LK Davis was omitted from the author line in this paper, which was later corrected by the authors of the paper, who listed her as the tenth author between ER Gamazon and L Osiecki.